Efficiency at maximum power: An analytically solvable model for stochastic heat engines
We study a class of cyclic Brownian heat engines in the framework of finite-time thermodynamics. For infinitely long cycle times, the engine works at the Carnot efficiency limit producing, however, zero power. For the efficiency at maximum power, we find
Feynman R. P. +6 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The research course in the estimation of productivity of cyclic steam stimulation wells can be divided into three stages: (a) the mobility of heavy oil in the cold area is neglected, (b) the mobility of heavy oil in the cold area is considered—however ...
Fengrui Sun, Yuedong Yao, Guozhen Li
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Enhancing isomer specificity in mass spectrometry by combining silver ion adduction and ion mobility
Background: Identification and characterization of steroids from complex mixtures with isomeric precision is key to studying endocrine-related metabolism and disorders.
Varun V. Sharma +3 more
doaj +1 more source
Frequency dependent deformation reversibility during cyclic loading
High-frequency testing (HFT) is useful for accelerated fatigue testing of conventional materials that typically serve under low-frequency loading conditions, as well as for the assessment of the robustness of microelectromechanical systems which ...
Shuai Shao +4 more
doaj +1 more source
How directional mobility affects biodiversity in rock-paper-scissors models
This work deals with a system of three distinct species that changes in time under the presence of mobility, selection, and reproduction, as in the popular rock-paper-scissors game.
Avelino, P. P. +5 more
core +1 more source
Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles [PDF]
Elevation of cAMP can cause gene-specific inhibition of interleukin 2 (IL-2) expression. To investigate the mechanism of this effect, we have combined electrophoretic mobility shift assays and in vivo genomic footprinting to assess both the availability ...
Chen, Dan, Rothenberg, Ellen V.
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Individual development depends not only on inherent qualities but also on the effective influence of the environment. The aim of this study was to compare the effect of variable intensity as partially regulated physical loads which are appropriate for ...
Arūnas Emeljanovas +2 more
doaj +1 more source

