Results 11 to 20 of about 1,916,855 (274)
Nature Communications, 2021 Despite recent success in computational design of structured cyclic peptides, de novo design of cyclic peptides that bind to any protein functional site remains difficult.
P. Hosseinzadeh +17 more
semanticscholar +2 more sources
Cyclic Peptides for the Treatment of Cancers: A Review
Molecules, 2022 Cyclic peptides have been widely reported to have therapeutic abilities in the treatment of cancer. This has been proven through in vitro and in vivo studies against breast, lung, liver, colon, and prostate cancers, among others.
D. Ramadhani +3 more
semanticscholar +3 more sources
Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies
Marine Drugs, 2022 Oceans are a rich source of structurally unique bioactive compounds from the perspective of potential therapeutic agents. Marine peptides are a particularly interesting group of secondary metabolites because of their chemistry and wide range of ...
R. Ribeiro +3 more
semanticscholar +3 more sources
Structural Diversity and Biological Activities of Fungal Cyclic Peptides, Excluding Cyclodipeptides
Molecules, 2017 Cyclic peptides are cyclic compounds formed mainly by the amide bonds between either proteinogenic or non-proteinogenic amino acids. This review highlights the occurrence, structures and biological activities of fungal cyclic peptides (excluding ...
Xiaohan Wang +4 more
semanticscholar +3 more sources
Natural Cyclic Peptides as an Attractive Modality for Therapeutics: A Mini Review
Molecules, 2018 Peptides are important biomolecules which facilitate the understanding of complex biological processes, which in turn could be serendipitous biological targets for future drugs. They are classified as a unique therapeutic niche and will play an important
M. Abdalla, L. Mcgaw
semanticscholar +3 more sources
Cyclic Peptides as Novel Therapeutic Microbicides: Engineering of Human Defensin Mimetics
Molecules, 2017 Cyclic peptides are receiving significant attention thanks to their antimicrobial activity and high serum stability, which is useful to develop and design novel antimicrobial agents.
A. Falanga +6 more
semanticscholar +3 more sources
Pharmaceuticals, 2023 Fungal infections remain a significant concern for human health. The emergence of microbial resistance, the improper use of antimicrobial drugs, and the need for fewer toxic antifungal treatments in immunocompromised patients have sparked substantial ...
Naiera M. Helmy, Keykavous Parang
doaj +1 more source
Bioinformatics-Assisted Discovery of Antioxidant Cyclic Peptides from Corn Gluten Meal. [PDF]
FoodsUsing a multidisciplinary approach, this paper was designed to prepare, identify, and characterize novel maize antioxidant cyclic peptides from protein hydrolysate of corn gluten meal (CGM).
Liu H +8 more
europepmc +2 more sources
Comparison of Collisional Fragmentation Pathways of Sodiated and Protonated Cyclic Peptide Analogs [PDF]
Zhipu Xuebao, 2023 Cyclic peptides and their related species have been shown a unique class of molecules characterized by their biological function and structural diversity.
DU Meng-ying1;JIAO Lu-yang1;XU Yi-cheng1;LI Shu-qi1;CUI Yong-liang1;ZHANG Sen1;KONG Xiang-lei1,2,3
doaj +1 more source
More than skin deep: cyclic peptides as wound healing and cytoprotective compounds
Frontiers in Cell and Developmental Biology, 2023 The prevalence and cost of wounds pose a challenge to patients as well as the healthcare system. Wounds can involve multiple tissue types and, in some cases, become chronic and difficult to treat.
Ying-Chiang J. Lee +3 more
doaj +1 more source