Results 31 to 40 of about 109,321 (266)

Including the normal to shear stresses ratio in fatigue life estimation for cyclic loadings [PDF]

open access: yesMATEC Web of Conferences, 2019
The paper presents the estimation of the fatigue life under multiaxial cyclic loading of two construction materials. The main aim of this paper is to present a new method which allows evaluation of fatigue life during the design and construction phase of machine elements. In paper three well known multiaxial fatigue criteria based on the critical plane
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Modeling the Effects of Particle Shape on Damping Ratio of Dry Sand by Simple Shear Testing and Artificial Intelligence

open access: yesApplied Sciences, 2023
This study investigates the effects of sand particle shape, in terms of roundness, sphericity and regularity, on the damping ratio of a dry sand material.
Abolfazl Baghbani   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The Effect of Fiber Orientation and Stress Ratio on the Crack Growth Behavior of Fiber Metal Laminates (FMLs)

open access: yesInternational Journal of Technology, 2018
The crack growth behavior of fiber metal laminates (FMLs) with fiber orientations of 90°/0° and 45°/45° to load direction was investigated with varying stress ratios of the cyclic constant load.
Anindito Purnowidodo   +3 more
doaj   +1 more source

Effect of normal stress on cyclic simple-shear behavior of gravel-structure interface

open access: yesRock and Soil Mechanics, 2021
The cyclic simple-shear behavior of soil-structure interfaces under different normal stresses is of great significance in theoretical analysis and engineering practices.
FENG Da-kuo, ZHANG Jian-min
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Experimental Study on the Effects of Initial Shear Stress and Vibration Frequency on Dynamic Strength of Saturated Sands

open access: yesAdvances in Materials Science and Engineering, 2019
The cyclic triaxial system is used to investigate the effects of confining pressure, initial shear stress, cyclic stress ratio, and vibration frequency on the dynamic strength characteristics of saturated sand in the Wenchuan area. Results show that when
Jian Zhang, Jiuting Cao, Sijie Huang
doaj   +1 more source

Deformation and cyclic resistance of sand in large-strain undrained torsional shear tests with initial static shear stress

open access: yesSoils and Foundations, 2021
This paper presents the findings from an experimental study focusing on the undrained cyclic behavior of sand in the presence of initial static shear stress.
Muhammad Umar   +3 more
doaj   +1 more source

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