Results 181 to 190 of about 504,196 (405)
Cyclin-dependent Kinase Inhibitor p16INK4A Inhibits Phosphorylation of RNA Polymerase II by General Transcription Factor TFIIH [PDF]
Hiroaki Serizawa
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Abstract Background N‐acetyltransferase 10 (NAT10) was reported to be associated with the immune microenvironment in several cancers. However, it is not known in pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the roles and mechanisms of NAT10 in tumor malignancy and the tumor microenvironment (TME) in PDAC.
Enhong Chen+11 more
wiley +1 more source
Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27Kip1 [PDF]
Keiju Hiromura+4 more
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Promising Prodiginins Biological Activities
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto+6 more
wiley +1 more source
Eugenia brasiliensis: Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential
Leaves of Eugenia brasiliensis were dried, crushed and macerated with polarity increment. The antiporliferative and anti‐migratory potential and the cell cycle were evaluated. 28 compounds were tentatively identified by mass sceptrometry. ABSTRACT This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against the HeLa
Giovana G. F. V. de Oliveira+9 more
wiley +1 more source
WAF1 Retards S-Phase Progression Primarily by Inhibition of Cyclin-Dependent Kinases
Vasily Ogryzko+2 more
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In Vivo Biosynthesis and Direct Incorporation of Non‐Canonical Amino Acids into Proteins
Autonomous cells are engineered biological systems capable of biosynthesising and directly incorporating non‐canonical amino acids (ncAAs) into proteins. These systems have the potential to extend the applicability of the genetic code to enable large‐scale fermentative production of proteins carrying ncAAs.
Ivana Drienovska+2 more
wiley +1 more source
Macromolecular High‐Affinity Binding Probed by Advanced Fluorescence Techniques
Due to the extreme sensitivity and the intrinsic selectivity of fluorescence techniques, high‐affinity binding can be measured even at extremely low molecule concentrations in the picomolar range. In particular, modern advanced techniques with fluorescence microscopes have provided considerable methodological advancements in recent years.
Alida Meyer+2 more
wiley +1 more source
Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C.
Jean‐Pierre Tassan+4 more
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