Pho85p, a Cyclin-Dependent Protein Kinase, and the Snf1p Protein Kinase Act Antagonistically To Control Glycogen Accumulation in Saccharomyces cerevisiae [PDF]
, 1996 Dongqing Huang +2 more
openalex +1 more source
Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly
Cytoskeleton, EarlyView.ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley +1 more source
Cell Reports, 2018 Summary: Protein translation in eukaryotes is cell-cycle dependent, with translation rates more robust in G1 phase of the cell cycle than in mitosis. However, whether the fundamental cell-cycle control machinery directly activates protein translation ...
Tai An +4 more
doaj
Cloning and characterization of the Xenopus cyclin-dependent kinase inhibitor p27XIC1.
, 1995 Jiyan Su +3 more
openalex +1 more source
Development of Novel Anticancer Pyrazolopyrimidinones Targeting Glioblastoma
ChemMedChem, Accepted Article.Glioblastoma (GBM) is the most common and aggressive malignant grade IV brain tumour and is one of the most difficult types of brain cancer to treat with a high incidence of resistance to traditionally used chemotherapeutics. Pyrazolopyrimidinones are fused nitrogen‐containing heterocyclic systems which are a scaffold in several bioactive drugs and ...
Kate Byrne +5 more
wiley +1 more source
Cell Reports, 2019 Summary: Pyruvate kinase is an important enzyme in glycolysis and a key metabolic control point. We recently observed a pyruvate kinase liver isoform (PKL) phosphorylation site at S113 that correlates with insulin resistance in rats on a 3 day high-fat ...
Brandon M. Gassaway +18 more
doaj
A Requirement for Cyclin D3–Cyclin-dependent Kinase (cdk)-4 Assembly in the Cyclic Adenosine Monophosphate–dependent Proliferation of Thyrocytes [PDF]
, 1998 Fabienne Depoortere +8 more
openalex +1 more source
Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27 Kip1
Cell, 1996 H. Kiyokawa +9 more
semanticscholar +1 more source
Bioinformatics analysis of immune‐programmed cell death‐related genes in nasopharyngeal carcinoma
Eye &ENT Research, EarlyView.Abstract Background Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor of the head and neck, characterized by a complex pathogenesis. Most newly diagnosed NPC patients are locally advanced, and 20%–30% of advanced NPC patients have poor immunotherapy results.
Hongqiang Chen +3 more
wiley +1 more source