Results 211 to 220 of about 550,507 (355)

Cyclin-dependent kinase inhibitor therapy for hematologic malignancies

Expert Opinion on Investigational Drugs, 2013
P. Bose, G. Simmons, S. Grant
semanticscholar   +1 more source

Deciphering the soybean root rot pathogen Phytophthora sojae: Signaling pathways, transcriptional regulation, and effector biology

New Plant Protection, EarlyView.
This review highlights how Phytophthora sojae utilizes unconventional lineage‐specific signaling networks, including unique G protein‐coupled receptor fusions, expanded kinases, and rapidly evolving effectors, to infect soybeans. Understanding these divergent molecular paradigms reveals critical vulnerabilities in this destructive pathogen, offering ...
Min Qiu, Xiaoyi Zhang, Bo Yang, Wenwu Ye, Yuanchao Wang   +4 more
wiley   +1 more source

The cyclin dependent kinase (CDK)7 inhibitor BS-181 inhibits pathogenic Cryptococcus species, causing G₂/M arrest and a splicing defect. [PDF]

Virulence
Sethiya P, Desmarini D, Bowring B, Dinh H, Cain AK, Parsania C, Halliday CL, Chen SC, Hewitt K, Djordjevic JT.   +9 more
europepmc   +1 more source

Cyclin-Dependent Kinase Inhibitor [PDF]

, 2020
openaire   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

An investigation on Alzheimer's disease with obstructive sleep apnea: alterations of cognitive function, roles of cyclin-dependent kinase 5 and changes of brain structure. [PDF]

Front Aging Neurosci
Luo D, Lian T, Wei N, Guo P, He M, Zhang Y, Huang Y, Liu G, Li J, Li J, Qi J, Guan H, Zhang W, Zhang W, Zheng Z, Yue H, Liu Z, Zhang F, Meng Y, Zhang W.   +19 more
europepmc   +1 more source

Cyclin-Dependent Kinase 5 [PDF]

, 2020
openaire   +1 more source

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

Proceedings of the National Academy of Sciences of the United States of America, 1996
T. Ohshima, Jerrold M. Ward, C. Huh, G. Longenecker, Veeranna, H. Pant, R. Brady, L. Martin, A. Kulkarni   +8 more
semanticscholar   +1 more source

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

PROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren, Kenneth Weke, Darryl Hardie, Mariya I. Goncheva, Ted Hupp, Javier Antonio Alfaro, Helena Pětrošová, David R. Goodlett   +7 more
wiley   +1 more source

Efficacy and Predictability of Cyclin-Dependent Kinase 4/6 Inhibitors in HER2-Positive Breast Cancer. [PDF]

Cancers (Basel)
Abbasi MS, Afzal MZ, Sarwar T, Gamlen-Steves HA.   +3 more
europepmc   +1 more source