Results 221 to 230 of about 550,507 (355)

Differential Roles for Cyclin-Dependent Kinase Inhibitors p21 and p16 in the Mechanisms of Senescence and Differentiation in Human Fibroblasts

Molecular and Cellular Biology, 1999
G. Stein, L. F. Drullinger, A. Soulard, V. Dulić   +3 more
semanticscholar   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Pan-cyclin-dependent kinase inhibition is a potential treatment for adenoid cystic carcinoma that downregulates the MYB::NFIB fusion and induces tumor regression. [PDF]

Cancer Commun (Lond)
Huang J, Larsson P, Kakay Afshari M, Tejera Nevado P, Tešan Tomić T, Fehr A, Jäwert F, Stenman G, Andersson MK.   +8 more
europepmc   +1 more source

Combining radiotherapy with CAR‐T cell therapy for solid tumors: Challenges, mechanisms, and future directions

Precision Radiation Oncology, EarlyView.
Radiotherapy enhances CAR‐Tcell therapy by increasing antigenicity, improving trafficking, and reshaping the tumor microenvironment. Despite its dual effects, including potential immune suppression, understanding these mechanisms enables the development of strategies to maximize synergy in solid tumors.
Leran Qiu, Xingyu Zhou, Jiao Xue, Xiaokang Zhang, Songbing Qin   +4 more
wiley   +1 more source

Targeting a Tau Kinase Cdk5, Cyclin-Dependent Kinase: A Blood-Based Diagnostic Marker and Therapeutic Earmark for Alzheimer's Disease. [PDF]

Biomolecules
Kumari S, Singh AK, Kumar M, Pradhan R, Rao AR, Yadav Y, Kumar P, Haldar P, Kaur P, Dey S.   +9 more
europepmc   +1 more source

Cyclin-Dependent Kinase 9 [PDF]

, 2020
openaire   +1 more source

Cyclin-Dependent Kinase Inhibitors [PDF]

, 2021
openaire   +1 more source

Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration

Proceedings of the National Academy of Sciences of the United States of America, 2012
M. K. Diril, Chandrahas Koumar Ratnacaram, V. Padmakumar, Tiehua Du, M. Wasser, V. Coppola, L. Tessarollo, P. Kaldis   +7 more
semanticscholar   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

PAK4 phosphorylates cyclin-dependent kinase 2 to promote the G₁/S transition during adipogenesis. [PDF]

Exp Mol Med
Yu HC, Park SH, Jo HJ, Sim H, Lee MR, Kim G, Park SY, Lee Y, Bae EJ, Park BH.   +9 more
europepmc   +1 more source