Results 221 to 230 of about 504,196 (405)

A Family of Cyclin-Like Proteins That Interact with the Pho85 Cyclin-Dependent Kinase [PDF]

open access: green, 1997
Vivien Measday   +6 more
openalex   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner   +7 more
wiley   +1 more source

Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2012
M. K. Diril   +7 more
semanticscholar   +1 more source

Mass cytometric detection of homologous recombination proficiency in circulating tumor cells to predict chemoresistance of metastatic breast cancer patients

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Circulating tumor cells can offer insights into treatment responses and metastatic recurrence, but current analysis methods are limited. Here, the authors tested a newly developed mass cytometry panel comprising biomarkers such as γH2AX and RAD51 in longitudinally monitored metastatic breast cancer patients.
Kathrin Niedermayer   +17 more
wiley   +1 more source

Cyclin Dependent Kinase 2 (CDK2) Inhibitors in Oncology Clinical Trials: A Review. [PDF]

open access: yesJ Immunother Precis Oncol
House I   +3 more
europepmc   +1 more source

Cyclin-Dependent Kinase Suppression by WEE1 Kinase Protects the Genome through Control of Replication Initiation and Nucleotide Consumption

open access: yesMolecular and Cellular Biology, 2012
Halfdan Beck   +10 more
semanticscholar   +1 more source

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