Results 171 to 180 of about 382,305 (392)

A Study of Skeletal Stem Cell Dynamics and Its Potential Applications in the Design of a Titanium Implant for Senile Osteoporosis

Advanced Science, EarlyView.
Senescent mesenchymal stromal cells (MSCs) drive age‐related osteoporosis (A‐OP) via adipogenic bias. Resveratrol, selected from transcriptome‐identified core genes, is delivered locally using GelMA‐chitosan hydrogel‐functionalised titanium implants. In A‐OP microenvironments, the hydrogel enables the sustained release of resveratrol, which reverses ...
Wuzhe Fan, Tao Zheng, Mingsong Mao, Pengfei Gao, Yulu Yang, Rong Wang, Yao Yang, Yangpeng Zuo, Tiantian Yuan, Ruqing Bai, Weihu Yang, Xingchen Yan, Kaiyong Cai   +12 more
wiley   +1 more source

A Family of Cyclin-Like Proteins That Interact with the Pho85 Cyclin-Dependent Kinase [PDF]

, 1997
Vivien Measday, Lynda Moore, Ravi Retnakaran, Jonguk Lee, Michael S. Donoviel, Aaron M. Neiman, Brenda Andrews   +6 more
openalex   +1 more source

Bioinspired Prolactin Pulse Release from Responsive Microneedles for Inhibiting Fatty Liver Formation

Advanced Science, EarlyView.
Inspired by the prolactin secretion profile under normal physiological conditions, biomimetic prolactin‐releasing microneedles are designed. Under the control of near infrared (NIR), these responsive microneedles facilitate pulsed release of prolactin to inhibit fatty liver formation.
Hongli Yin, Wenjuan Tang, Danqing Huang, JingJing Gan, Pengzi Zhang, Yuanjin Zhao, Yan Bi   +6 more
wiley   +1 more source

A curious case of cyclin-dependent kinases in neutrophils. [PDF]

J Leukoc Biol, 2022
Syahirah R, Hsu AY, Deng Q.
europepmc   +1 more source

Acute 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure Results in Enhanced Tyrosylphosphorylation and Expression of Murine Hepatic Cyclin Dependent Kinases

, 1993
Xiangyuan Ma, John G. Babish
openalex   +1 more source

The Epstein-Barr virus bZIP transcription factor Zta causes G0/G1 cell cycle arrest through induction of cyclin-dependent kinase inhibitors. [PDF]

, 1996
Corinne Cayrol, Erik K. Flemington
openalex   +1 more source

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

Targeting cyclin-dependent kinases in sarcoma treatment: Current perspectives and future directions. [PDF]

Front Oncol, 2023
Merlini A, Pavese V, Manessi G, Rabino M, Tolomeo F, Aliberti S, D'Ambrosio L, Grignani G.   +7 more
europepmc   +1 more source

Long noncoding RNA GCH1 mediates mitophagy via the PTEN‐induced kinase 1/Parkin pathway to drive chondrocyte dysfunction and cartilage degeneration in osteoarthritis

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract illustrates the role of lncRNA‐GCH1 in regulating mitophagy and its downstream effects on chondrocyte dysfunction and cartilage degradation in osteoarthritis (OA). Elevated lncRNA‐GCH1 stabilizes PINK1 protein, enhancing mitophagy and mitochondrial turnover.
Gang Zeng, Yujun Sun, Taihe Liu, Wenzhou Liu, Yanbo Chen, Jionglin Wu, Jiayuan Zheng, Weidong Song, Yue Ding   +8 more
wiley   +1 more source

Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases.

, 1993
Yan Geng, Robert A. Weinberg
openalex   +1 more source