The Yeast Carboxyl-Terminal Repeat Domain Kinase CTDK-I Is a Divergent Cyclin–Cyclin-Dependent Kinase Complex [PDF]
David E. Sterner+3 more
openalex +1 more source
Two efficient methods, generalized many‐body expansion for building density matrices (GMBE‐DM) and D3‐ML, are introduced for ranking protein–ligand binding affinities. GMBE‐DM delivers quantum‐accurate results within minutes, while D3‐ML achieves even higher accuracy in under one second per complex.
Ka Un Lao, Danyang Wang
wiley +1 more source
Targeting Mediator Kinase Cyclin-Dependent Kinases 8/19 Potentiates Chemotherapeutic Responses, Reverses Tumor Growth, and Prolongs Survival from Ovarian Clear Cell Carcinoma. [PDF]
Barton WC+9 more
europepmc +1 more source
Signaling through cyclin D-dependent kinases
Yj Choi, L. Anders
semanticscholar +1 more source
Bioinformatics analysis of immune‐programmed cell death‐related genes in nasopharyngeal carcinoma
Abstract Background Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor of the head and neck, characterized by a complex pathogenesis. Most newly diagnosed NPC patients are locally advanced, and 20%–30% of advanced NPC patients have poor immunotherapy results.
Hongqiang Chen+3 more
wiley +1 more source
Cyclin-dependent kinases (CDKs) are key genes regulating early development of Neptunea arthritica cumingii: evidence from comparative transcriptome and proteome analyses. [PDF]
Lv F, Ge X, Chang Y, Hao Z.
europepmc +1 more source
Phosphorylation of mixed lineage kinase MLK3 by cyclin-dependent kinases CDK1 and CDK2 controls ovarian cancer cell division. [PDF]
Cedeno-Rosario L+5 more
europepmc +1 more source
G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts [PDF]
Lisa Connell‐Crowley+2 more
openalex +1 more source
DMAPO/Boc2O‐Mediated One‐Pot Direct N‐Acylation of Sulfoximines with Carboxylic Acids
This report describes a general and simple method for the one‐pot direct N‐acylation of sulfoximines with carboxylic acids using our previously developed 4‐(N,N‐dimethylamino)pyridine N‐oxide (DMAPO)/di‐tert‐butyl dicarbonate (Boc2O) system. The method can be performed under mild low‐temperature reaction conditions and has a wide substrate scope.
Atsushi Umehara+2 more
wiley +1 more source