Results 211 to 220 of about 403,677 (344)

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

The Multiple Personalities of the Regulatory Subunit of Protein Kinase CK2: CK2 Dependent and CK2 Independent Roles Reveal a Secret Identity for CK2β

open access: yesInternational Journal of Biological Sciences, 2005
Protein kinase CK2 (formerly casein kinase II), an enzyme that participates in a wide variety of cellular processes, has traditionally been classified as a stable tetrameric complex consisting of two catalytic CK2α or CK2α' subunits and two ...
doaj  

Yeast culture in weaned lamb feed: a proteomic journey into enhanced rumen health and growth. [PDF]

open access: yesJ Anim Sci Biotechnol
Li X   +9 more
europepmc   +1 more source

NAT10 regulates tumor progression and immune microenvironment in pancreatic ductal adenocarcinoma via the N4‐acetylated LAMB3‐mediated FAK/ERK pathway

open access: yesCancer Communications, EarlyView.
Abstract Background N‐acetyltransferase 10 (NAT10) was reported to be associated with the immune microenvironment in several cancers. However, it is not known in pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the roles and mechanisms of NAT10 in tumor malignancy and the tumor microenvironment (TME) in PDAC.
Enhong Chen   +11 more
wiley   +1 more source

A novel peptide 66CTG stabilizes Myc proto-oncogene protein to promote triple-negative breast cancer growth. [PDF]

open access: yesSignal Transduct Target Ther
Liang H   +17 more
europepmc   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

open access: yesCancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu   +16 more
wiley   +1 more source

Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer. [PDF]

open access: yesCancer Discov
Shirole NH   +15 more
europepmc   +1 more source

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