Results 211 to 220 of about 230,940 (319)

Exploring recent advances in signaling pathways and hallmarks of uveal melanoma: a comprehensive review. [PDF]

Explor Target Antitumor Ther
Banimohammad M, Khalafi P, Gholamin D, Bangaleh Z, Akhtar N, Solomon AD, Prabhakar PK, Sanami S, Prakash A, Pazoki-Toroudi H.   +9 more
europepmc   +1 more source

HN1 expression contributes to mitotic fidelity through Aurora A‐PLK1‐Eg5 axis

Cytoskeleton, EarlyView.
Abstract Hematological and neurological expressed 1 (HN1) is homolog of Jupiter protein from Drosophila melanogaster where it functions as a microtubule‐associated protein. However, in mammalian cells, HN1 is associated partially with y‐tubulin in centrosomes, Stathmin for stabilizing microtubules, and Cdh1 for regulating Cyclin B1 for cell cycle ...
Gülseren Özduman, Faruk Şimşek, Aadil Javed, Kemal Sami Korkmaz   +3 more
wiley   +1 more source

Vascular perfusion differs in two distinct PDGFRβ‐positive zones within the ischemic core of male mice 2 weeks following photothrombotic stroke

Journal of Neuroscience Research, Volume 101, Issue 2, Page 278-292, February 2023., 2023
Blood vessels in the ischemic core and peri‐lesion are capable of flow 2 weeks post‐photothrombotic stroke. There are two PDGFRβ‐positive zones within the ischemic core, one which resembles fibrotic scarring, adjacent to a GFAP‐positive peri‐lesion, whereas the other is primarily vessel associated.
Gary P. Morris, Emma K. Gowing, Jo‐Maree Courtney, Hannah E. Coombe, Natalie E. King, Sarah S. J. Rewell, David W. Howells, Andrew N. Clarkson, Brad A. Sutherland   +8 more
wiley   +1 more source

Inhibition of Cyclin D1 by Novel Biguanide Derivative YB-004 Increases the Sensitivity of Bladder Cancer to Olaparib via Causing G0 / G1 Arrest. [PDF]

Int J Biol Sci
Xiao D, Chu X, Wang W, Peng M, Lv Q, Xu C, Duan H, Yang X.   +7 more
europepmc   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

Cytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source

Carotenoids Modulate FoxO-Induced Cell Cycle Awrrest in Human Cancer Cell Lines: A Scoping Review. [PDF]

Food Sci Nutr
Lee ZX, Guo H, Looi AD, Bhuvanendran S, Magalingam KB, Lee WL, Radhakrishnan AK.   +6 more
europepmc   +1 more source

Herpes simplex virus 1 alpha regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3 [PDF]

, 1997
Yasushi Kawaguchi, C. Van Sant, Bernard Roizman   +2 more
openalex   +1 more source

Lamellarin D Acts as an Inhibitor of Type I Collagen Production

ChemMedChem, EarlyView.
COL1A2 gene, encoding type I collagen, is a key target for pulmonary fibrosis. We established a screening system to identify small molecules that inhibit COL1A2 gene expression. Using this system, we screen a library of compounds and identify lamellarin D as a potent inhibitor of COL1A2 expression, suggesting lamellarin D is a promising new lung ...
Daisuke Okuno, Noriho Sakamoto, Hideki Hayashi, Tsutomu Fukuda, Yoshiko Akiyama, Chiaki Iketani, Ritsuko Murakami, Takatomo Tokito, Takuto Miyamura, Hirokazu Yura, Takashi Kido, Hiroshi Ishimoto, Shinnosuke Takemoto, Takahiro Takazono, Tomoya Nishino, Yuji Ishimatsu, Jun Ishihara, Kohsuke Takeda, Yoshimasa Tanaka, Hiroshi Mukae   +19 more
wiley   +1 more source

Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors. [PDF]

Cancer Res
House NC, Brown VE, Chen M, Yuan L, Moore SL, Guo J, Choi YJ, Muthuswamy L, Ribich S, Ramsden P, Faia KL.   +10 more
europepmc   +1 more source

Chemically induced premature mitosis: differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation.

, 1991
Kathleen E. Steinmann, Glenn S. Belinsky, D Lee, Robert Schlegel   +3 more
openalex   +1 more source