Results 251 to 260 of about 483,027 (406)

F-box protein FBXO32 ubiquitinates and stabilizes D-type cyclins to drive cancer progression. [PDF]

Nat Commun
Li F, Yu H, Zhang Y, Ma Y, Chen X, Zhang J, Sun L, Guo R, Wu Y, Zheng P, Wang X, Bie P, He F, Zhang L, Xie C, Xiong H.   +15 more
europepmc   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Cancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae, Megan Othus, Sandip Pravin Patel, Raid Aljumaily, Khine Z. Win, Tanya Pejovic, Sajeve S. Thomas, William R. Robinson III, Hye Sung Kim, Liam Il‐Young Chung, Christine M. McLeod, Helen X. Chen, Elad Sharon, Howard Streicher, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock   +16 more
wiley   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

The Multiple Personalities of the Regulatory Subunit of Protein Kinase CK2: CK2 Dependent and CK2 Independent Roles Reveal a Secret Identity for CK2β

International Journal of Biological Sciences, 2005
Protein kinase CK2 (formerly casein kinase II), an enzyme that participates in a wide variety of cellular processes, has traditionally been classified as a stable tetrameric complex consisting of two catalytic CK2α or CK2α' subunits and two ...
doaj  

Niclosamide: CRL4^AMBRA1 mediated degradation of cyclin D1 following mitochondrial membrane depolarization. [PDF]

RSC Med Chem
Coomar S, Gasser JA, Słabicki M, Donovan KA, Fischer ES, Ebert BL, Gillingham D, Thomä NH.   +7 more
europepmc   +1 more source

Chemically induced premature mitosis: differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation.

, 1991
Kathleen E. Steinmann, Glenn S. Belinsky, D Lee, Robert Schlegel   +3 more
openalex   +1 more source

Cyclin-like accumulation and loss of the putative kinetochore motor CENP-E results from coupling continuous synthesis with specific degradation at the end of mitosis. [PDF]

, 1994
Kevin D. Brown, Richard Coulson, Tim J. Yen, Don W. Cleveland   +3 more
openalex   +1 more source

Quitting Your Day Job in Response to Stress: Cell Survival and Cell Death Require Secondary Cytoplasmic Roles of Cyclin C and Med13. [PDF]

Cells
Bauer JR, Robinson TL, Strich R, Cooper KF.   +3 more
europepmc   +1 more source

Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells.

, 1994
Hiroaki Kiyokawa, Victoria M. Richon, Richard A. Rifkind, P A Marks   +3 more
openalex   +1 more source

Phytochemical Investigation and Biological Evaluation of Disynaphia filifolia: A Novel Source of Tremetone in Asteraceae

Chemistry &Biodiversity, EarlyView.
ABSTRACT Chemical investigation of Disynaphia filifolia (Hassl.) R.M. King & H. Rob. (Asteraceae) led to the isolation of eight compounds, with tremetone being the major metabolite recovered. Tremetone has been suggested as the toxic compound in Ageratina altissima and Isocoma pluriflora, two species of the Asteraceae family. Although D.
Yasmin Rodrigues Chierici, Anderson Valdiney Gomes Ramos, Drielli Rhiane Peres Colhado Areas, Alana Carla Battistella, Solange Maria Cottica, Tatiana Shioji Tiuman, Helena Mannochio‐Russo, Ana Lucia Tasca Gois Ruiz, Mary Ann Foglio, Marta Regina Barrotto do Carmo, Maria Helena Sarragiotto, Debora Cristina Baldoqui   +11 more
wiley   +1 more source