Results 251 to 260 of about 403,677 (344)

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state [PDF]

, 1995
Christian Dahmann, John F.X. Diffley, Kim Nasmyth   +2 more
openalex   +1 more source

Bioinformatics analysis of immune‐programmed cell death‐related genes in nasopharyngeal carcinoma

Eye &ENT Research, EarlyView.
Abstract Background Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor of the head and neck, characterized by a complex pathogenesis. Most newly diagnosed NPC patients are locally advanced, and 20%–30% of advanced NPC patients have poor immunotherapy results.
Hongqiang Chen, Zhe Zhang, Xueting Yang, Chao Li   +3 more
wiley   +1 more source

Folate-based binuclear Mn(II) chelates with 2,2'-bipyridine/1,10-phenanthroline as targeted anticancer agents for colon cancer cells. [PDF]

Sci Rep
Ragab MS, Soliman MH, Sharaky MM, Saad A, Shehata MR, Shoukry MM, Ragheb MA.   +6 more
europepmc   +1 more source

DMAPO/Boc2O‐Mediated One‐Pot Direct N‐Acylation of Sulfoximines with Carboxylic Acids

European Journal of Organic Chemistry, Accepted Article.
This report describes a general and simple method for the one‐pot direct N‐acylation of sulfoximines with carboxylic acids using our previously developed 4‐(N,N‐dimethylamino)pyridine N‐oxide (DMAPO)/di‐tert‐butyl dicarbonate (Boc2O) system. The method can be performed under mild low‐temperature reaction conditions and has a wide substrate scope.
Atsushi Umehara, Sukenao Kawai, Makoto Sasaki   +2 more
wiley   +1 more source

Evaluating the Role of Genetic Markers in Predicting Oral Leukoplakia Malignancy Transformation.

J Pharm Bioallied Sci
Qurishi AA, Morsy MSM, Atout AM, Abzoah SE, Wadani MHM, Ghazwani NHA, Jafari SAM.   +6 more
europepmc   +1 more source

Stathmin Serine 16 Phosphorylation Is a Key Regulator of Cell Cycle Progression Without Activating Migration and Invasion In Vitro. [PDF]

Cancers (Basel)
Deford PL, VonHandorf AP, Hunt BG, Venkatraman S, Waltz SE, Burns KA, Kasper S.   +6 more
europepmc   +1 more source

Degradation of the proto-oncogene product p39mos is not necessary for cyclin proteolysis and exit from meiotic metaphase: requirement for a Ca(2+)-calmodulin dependent event.

, 1991
Thierry Lorca, Simon Galas, Didier Fesquet, Alain Devault, J C Cavadore, M. Dorée   +5 more
openalex   +1 more source

Critical Evaluation of Methods for the Identification of Aneugens

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun, Stephen D. Dertinger, Azeddine Elhajouji, Daniel J. Roberts, Jan van Benthem, Maik Schuler, Shambhu Roy, Alexandra Taraboletti, Connie L. Chen   +8 more
wiley   +1 more source

Targeting CDKs in cancer therapy: advances in PROTACs and molecular glues. [PDF]

NPJ Precis Oncol
Marei HE, Bedair K, Hasan A, Al-Mansoori L, Gaiba A, Morrione A, Cenciarelli C, Giordano A.   +7 more
europepmc   +1 more source

Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

Exploration, EarlyView.
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li, Qiuye Jia, Naixin Liu, Saige Yin, Junyuan Wang, Yujing Ding, Yuliu Yang, Ying Peng, Zeqiong Ru, Shaoyang Zhang, Bu'er Qi, Jun Sun, Li He, Ying Wang, Kun Guo, Xinwang Yang   +15 more
wiley   +1 more source