Results 121 to 130 of about 242,314 (247)

Cyclin-Dependent Kinase Inhibitors as Marketed Anticancer Drugs: Where Are We Now? A Short Survey [PDF]

, 2014
Gaëlle Mariaule, Philippe Belmont
openalex   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Engineering Immortalized Bovine Granulosa Cells Using a Triple-Gene Approach: Mutant CDK4, Cyclin D1, and TERT. [PDF]

Cell Biol Int
Bai L, Takahashi M, Kobayashi J, Eitsuka T, Matsusaka H, Ozaki T, Sugano E, Tomita H, Xu Y, Kawamura K, Nakagawa K, Kiyono T, Fukuda T.   +12 more
europepmc   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Expression of Cyclin D1, p53, and Tumor-Associated Tissue Eosinophils in Different Grades of Oral Squamous Cell Carcinoma. [PDF]

Cureus
Habib M, Rauf M, Omair S, Chaudry SS, Khan AR, Ahmad A, Sheikh A.   +6 more
europepmc   +1 more source

The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing [PDF]

, 2008
Hanh H. Nguyen, Ida Aronchik, Gloria A. Brar, David H.H. Nguyen, Leonard F. Bjeldanes, Gary L. Firestone   +5 more
openalex   +1 more source

Multifunctional H2S‐activated metal‐organic framework systems for targeted colorectal cancer imaging and synergistic copper‐induced tumor regression

BMEMat, EarlyView.
The in situ reaction of Cu‐MOFs with endogenous H2S enabled PA imaging and facilitated combined PTT/chemotherapy for colorectal cancer therapy. Abstract Stimuli‐responsive nanomaterials offer significant potential for enhancing diagnostic accuracy, optimizing therapeutic efficacy, and advancing precision theranostics.
Nannan Zheng, Qinghui Wang, Zhiyue Cao, Chao Yu, Renkai Zhang, Kaiyan Xiang, Haoguang Wu, Kai Li, Qianqian Ni, Qiuyue Ma, Jing Mu, Xiaoyuan Chen, Liangcan He, Shaoqin Liu   +13 more
wiley   +1 more source

Sumoylation of cyclin and its therapeutic potential for cancer. [PDF]

Anim Cells Syst (Seoul)
Ryu HY, Hochstrasser M.
europepmc   +1 more source

膀胱移行上皮癌におけるPCNA/cyclin, p53, C-erbB-2の発現と組織学的悪性度に関する検討

, 1995
裕康 吉川, 隆夫 池内, 宏 井口, 恭忠 小野寺, 祥生 甲斐   +4 more
openalex   +1 more source

Data from Inhibition of NF-κB–Mediated Signaling by the Cyclin-Dependent Kinase Inhibitor CR8 Overcomes Prosurvival Stimuli to Induce Apoptosis in Chronic Lymphocytic Leukemia Cells

, 2023
Emilio Cosimo, Alison M. McCaig, Luke J.M. Carter-Brzezinski, Helen Wheadon, Michael T. Leach, Karine Le Ster, Christian Berthou, Émilie Durieu, Nassima Oumata, Hervé Galons, Laurent Meijer, Alison M. Michie   +11 more
openalex   +1 more source