Results 211 to 220 of about 22,958,501 (389)

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

open access: yesCancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae   +16 more
wiley   +1 more source

Activation of p34cdc2 kinase by cyclin A. [PDF]

open access: bronze, 1991
Linda Roy   +6 more
openalex   +1 more source

Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2010
Gaetan Pascreau   +3 more
semanticscholar   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

open access: yesCancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang   +6 more
wiley   +1 more source

Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells.

open access: green, 1994
Hiroaki Kiyokawa   +3 more
openalex   +1 more source

Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts.

open access: hybrid, 1991
Avram Hershko   +4 more
openalex   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

SLC1A5-dependent glutamine uptake in hepatocytes promotes liver regeneration. [PDF]

open access: yesHepatol Commun
Duan Y   +16 more
europepmc   +1 more source

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