Results 241 to 250 of about 22,968,325 (388)

The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition.

, 1990
William G. F. Whitfield, Cayetano González, Gabriela Maldonado-Codina, David M. Glover   +3 more
openalex   +1 more source

Activation of FoxM1 during G2 Requires Cyclin A/Cdk-Dependent Relief of Autorepression by the FoxM1 N-Terminal Domain

Molecular and Cellular Biology, 2008
J. Laoukili, M. Álvarez, L. Meijer, M. Stahl, S. Mohammed, L. Kleij, A. Heck, R. Medema   +7 more
semanticscholar   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Mechanism of D-type cyclin recognition by the AMBRA1 E3 ligase receptor. [PDF]

Sci Adv
Wang Y, Liu M, Wang S, Mai X, Wang X, Teng F, Lyu T, Su MY, Stjepanovic G.   +8 more
europepmc   +1 more source

Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events

Oncogene, 2008
L. Boer, Vanessa Oakes, Heather Beamish, Nichole Giles, Frankie Stevens, Maria J Somodevilla-Torres, Colin P.C. DeSouza, Brian Gabrielli   +7 more
semanticscholar   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Cancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae, Megan Othus, Sandip Pravin Patel, Raid Aljumaily, Khine Z. Win, Tanya Pejovic, Sajeve S. Thomas, William R. Robinson III, Hye Sung Kim, Liam Il‐Young Chung, Christine M. McLeod, Helen X. Chen, Elad Sharon, Howard Streicher, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock   +16 more
wiley   +1 more source

Heat stress affects expression levels of circadian clock gene Bmal1 and cyclins in rat thoracic aortic endothelial cells. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Chang X, Zhang H, Cao H, Hou L, Meng X, Tao H, Luo Y, Li G.   +7 more
europepmc   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis. [PDF]

iScience
Akatsuka H, Kashikawa T, Masuhara K, Tokusanai M, Li C, Iida Y, Okada-Yamaguchi C, Okada Y, Tanaka M, Suzuki T, Yamamoto N, Hozumi K, Tanaka T, Nakaoka H, Hosomichi K, Hamaguchi Y, Hamada M, Shiraishi Y, Kamiya A, Nakamura Y, Harada K, Ibrahim AA, Yahata T, Ohtsuka M, Nakamura N, Hosokawa H, Kimura M, Inoue I, Sato T.   +28 more
europepmc   +1 more source

Phosphorylation of mammalian CDC6 by Cyclin A/CDK2 regulates its subcellular localization

EMBO Journal, 1999
B. O. Petersen, J. Lukas, C. Sørensen, J. Bartek, K. Helin   +4 more
semanticscholar   +1 more source