BMX inhibition overcomes small cell lung cancer chemoresistance by stabilizing E2F1 via ERK1/2-Cyclin D1/CDK4/6 axis. [PDF]
Wu T +11 more
europepmc +1 more source
Costunolide Induces Apoptosis via Modulation of Cyclin-Dependent Kinase in HL-60 Human Leukemia Cells [PDF]
Dong Hee Kim +4 more
openalex +1 more source
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho +7 more
wiley +1 more source
Tumor cell cycle regulation: integrated perspective of stage characteristics, regulatory networks, and signaling pathway intervention strategies. [PDF]
Wan Q +6 more
europepmc +1 more source
The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning. [PDF]
Anna Philpott +3 more
openalex +1 more source
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon +5 more
wiley +1 more source
Ubiquitin C-terminal hydrolase L3 promotes liver cancer cell proliferation by modulating the AMP-activated protein kinase signaling pathway. [PDF]
Liu Y +8 more
europepmc +1 more source
Nuclear loss of protein arginine N-methyltransferase 2 in breast carcinoma is associated with tumor grade and overexpression of cyclin D1 protein [PDF]
Jing Zhong +14 more
openalex +1 more source
What's New? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado +54 more
wiley +1 more source
Glutamate decarboxylase 1 (GAD1) suppresses the progression of glioblastoma through GSK3β/β-catenin pathway. [PDF]
Zheng Y, Zhong Z, Zhang C, Gu J.
europepmc +1 more source

