Results 271 to 280 of about 406,416 (358)

[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells <i>in vitro</i> and affects expression of cyclin D1 and MMP‑9. [PDF]

Oncol Rep
Yuan Z, Sanders AJ, Ye L, Wang Y, Jiang WG.   +4 more
europepmc   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Molecular Regulation of Cardiomyocyte Cell Cycle and Regeneration. [PDF]

Biology (Basel)
Li F, Son Y, Yang M, Zhu W.
europepmc   +1 more source

Dasatinib and quercetin prevent alveolar bone loss in aged mice

Journal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli, Renata M. Moraes, Yuri C. Santos, Jaqueline L. Ribeiro, Maíra T. Garcia, Renata F. Prado, Florent Elefteriou, Ana Lia Anbinder   +7 more
wiley   +1 more source

NFIC suppressed the development of Glioma via modulating the balance of SHP2/PI3K and NF-κB/PTEN Signaling. [PDF]

PLoS One
Bao H, Liu K, Gao N, Su Y, Bai H, Dou C, Jiang F, Wang F.   +7 more
europepmc   +1 more source

Aging and periodontitis increase brain dissemination of oral bacteria

Journal of Periodontology, EarlyView.
Abstract Background The microbiome is a dynamic system that changes throughout life. Studies have revealed the relationship between periodontal disease and the oral microbiota; however, the impact of periodontal disease on the expression of senescence markers and on the inflammaging of the oral and systemic microbiome remains unclear.
Ozge Unlu, Tsute Chen, Nil Yakar, Zeliha Guney, Bruce Paster, Isabel Carreras, Alpaslan Dedeoglu, Alpdogan Kantarci   +7 more
wiley   +1 more source

Orally Bioavailable Cyclin A/B RxL Inhibitors: Optimization of a Novel Class of Macrocyclic Peptides That Target E2F-High and G1-S-Checkpoint-Compromised Cancers. [PDF]

J Med Chem
Shapiro JA, Dupper NJ, Fraga-Walton B, Bockus AT, Leung SSF, Yang K, Bhatt C, DeMart MK, Baldomero MP, Hernandez L, Fung G, Metobo S, Xie S, Lent BM, Spellmeyer DC, Luna J, Hoang D, Chand M, Gritsenko Y, Gleason CE, Hamkins-Indik F, Zheng J, Odeh R, Nosrati M, He D, Bambal R, Cremin P, Fang J, Levin B, Wang EW, Evangelista M, Earp D, Kreatsoulas C, Singh R, Garcia PD, Aggen JB.   +35 more
europepmc   +1 more source

Case series: Joubert syndrome and eosinophilic esophagitis

JPGN Reports, EarlyView.
Abstract Joubert syndrome (JS) is a rare genetic disorder characterized by developmental abnormalities, particularly in the brainstem and cerebellar vermis, alongside multisystem manifestations such as kidney and liver anomalies, polydactyly, cleft lip or palate, and tongue defects.
Jonathon Schening, Stephanie Leon‐Paredes, Eric Chiou, Vibha Szafron, Anthony Olive, Sara Anvari   +5 more
wiley   +1 more source

Baloxavir Acid-Induced Mitochondrial Toxicity and Cell Cycle Arrest Contribute to Its Adverse Effects. [PDF]

Int J Mol Sci
Zhan P, Ren Y, Han K, Jin G, Yang Y, Shi L, Ci Y.   +6 more
europepmc   +1 more source

Transient proliferation by reversible YAP and mitogen control of the cyclin D1/p27 ratio. [PDF]

Commun Biol
Ferrick KR, Upadhya SW, Fan Y, Ratnayeke N, Teruel MN, Meyer T.   +5 more
europepmc   +1 more source