Cyclin B and Cyclin A Confer Different Substrate Recognition Properties on CDK2
N. Brown+5 more
semanticscholar +1 more source
Macromolecular High‐Affinity Binding Probed by Advanced Fluorescence Techniques
For interacting biomolecules in solution, confocal fluorescence microscopy enables some very effective approaches to characterize intermolecular binding in complex sample environments and with small sample consumption. These approaches range from fluorescence‐based genetically encoded biosensors for use in living cells to the high controllability in ...
Alida Meyer+2 more
wiley +1 more source
Thyroid hormone suppresses cell growth by regulating CDK2 and cyclin E1 expression via Hepsin. [PDF]
Lin YH+5 more
europepmc +1 more source
Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley +1 more source
Toxicity and mechanism of bis(2-ethylhexyl) phthalate in premature ovarian failure: A network toxicology prediction and molecular docking analysis. [PDF]
Ge S, Li Q, Li Y, Cao C, Shi Y, Chen Y.
europepmc +1 more source
Cyclin B1 Expression in HeLa S3 Cells Studied by Flow Cytometry
Steven W. Sherwood+3 more
openalex +1 more source
Development of Novel Anticancer Pyrazolopyrimidinones Targeting Glioblastoma
Glioblastoma (GBM) is the most common and aggressive malignant grade IV brain tumour and is one of the most difficult types of brain cancer to treat with a high incidence of resistance to traditionally used chemotherapeutics. Pyrazolopyrimidinones are fused nitrogen‐containing heterocyclic systems which are a scaffold in several bioactive drugs and ...
Kate Byrne+5 more
wiley +1 more source
Development of CDK4/6 Inhibitors in Gastrointestinal Cancers: Biomarkers to Move Forward. [PDF]
Voutsadakis IA.
europepmc +1 more source