Results 151 to 160 of about 13,616,203 (256)

A link between MAP kinase and p34cdc2/cyclin B during oocyte maturation: p90rsk phosphorylates and inactivates the p34cdc2 inhibitory kinase Myt1 [PDF]

, 1998
Amparo Palmer
openalex   +1 more source

Cleft Palate Induced by Mycophenolate Mofetil Is Associated with miR-4680-3p and let-7c-5p in Human Palate Cells

Non-Coding RNA
Background/Objectives: Cleft palate is a birth defect associated with environmental and genetic factors. Disturbance of microRNAs (miRNAs) and exposure to medicinal agents during pregnancy can cause cleft palate.
Hiroki Yoshioka, Hanane Horita, Yosuke Tsukiboshi, Hisaka Kurita, Aya Ogata, Kenichi Ogata   +5 more
doaj   +1 more source

Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation. [PDF]

Nat Commun, 2021
Song X, Conti D, Shrestha RL, Braun D, Draviam VM.   +4 more
europepmc   +1 more source

Decapentaplegic is required for arrest in G1 phase during Drosophila eye development [PDF]

, 1998
During eye development in Drosophila, cell cycle progression is coordinated with differentiation. Prior to differentiation, cells arrest in G1 phase anterior to and within the morphogenetic furrow.
Hoffman, F. Michael, Horsfield, Julie A., Penton, Andrea, Richardson, Helena Elizabeth, Secombe, Julie   +4 more
core  

A Mathematical Model of the Cell Cycle: Exploring the Impact of Zingerone on Cancer Cell Proliferation [PDF]

arXiv
This paper presents a mathematical model that explores the interactions between Cyclin-Dependent Kinase 1 (CDK1) and the Anaphase-Promoting Complex (APC) in cancer cells. Through the analysis of a dynamical system simulating the CDK1-APC network, we investigate the system's behavior and its implications for cancer progression and potential therapeutic ...
arxiv  

The Novel Cyclin-Dependent Kinase Inhibitor Flavopiridol Downregulates Bcl-2 and Induces Growth Arrest and Apoptosis in Chronic B-Cell Leukemia Lines [PDF]

, 1997
Andrea König, Gary K. Schwartz, Ramzi M. Mohammad, Ayad Al‐Katib, Janice Gabrilove   +4 more
openalex   +1 more source

Cyclin E1 overexpression triggers interferon signaling and is associated with antitumor immunity in breast cancer

Journal for ImmunoTherapy of Cancer
Background Cyclin E1 overexpression drives oncogenesis in several cancers through deregulation of DNA replication and induction of genomic instability, which may potentially trigger immune signaling via cytoplasmic DNA.
Bert van der Vegt, Carolien P Schroder, Rudolf S N Fehrmann, Shibo Yu, Chantal Stappenbelt, Mengting Chen, Mirte Dekker, Arkajyoti Bhattacharya, Tineke van der Sluis, Mieke C Zwager, Marcel A T M van Vugt   +10 more
doaj   +1 more source

Molecule Generation for Target Protein Binding with Hierarchical Consistency Diffusion Model [PDF]

arXiv
Effective generation of molecular structures, or new chemical entities, that bind to target proteins is crucial for lead identification and optimization in drug discovery. Despite advancements in atom- and motif-wise deep learning models for 3D molecular generation, current methods often struggle with validity and reliability.
arxiv  

Selective modulation of the cyclin B/CDK1 and cyclin D/CDK4 complexes during in vitro human megakaryocyte development [PDF]

, 1999
Alessandra Bassini, Sabina Pierpaoli, Elisabetta Falcieri, Marco Vitale, Lia Guidotti, Silvano Capitani, Giorgio Zauli   +6 more
openalex   +1 more source

TGF-β1 Induces the Cyclin-Dependent Kinase Inhibitor p27Kip1 mRNA and Protein in Murine B Cells [PDF]

, 1998
H Kamesaki, Kimiko Nishizawa, Ginette Y. Michaud, Jeffrey Cossman, Tohru Kiyono   +4 more
openalex   +1 more source