Results 61 to 70 of about 12,781,724 (361)
Exploring cell cycle-mediated regulations of glycolysis in budding yeast
Frontiers in Microbiology, 2023 Coordination of cell cycle with metabolism exists in all cell types that grow by division. It serves to build a new cell, (i) fueling building blocks for the synthesis of proteins, nucleic acids, and membranes, and (ii) producing energy through ...
Yanfei Zhang +4 more
doaj +1 more source
Journal of Biological Chemistry, 2012 Background: Pah1p, a phosphatidate phosphatase in yeast, produces diacylglycerol for lipid synthesis. Results: Phosphorylation of Pah1p by protein kinase A inhibited membrane association, phosphatidate phosphatase activity, and triacylglycerol synthesis.
Wen‐Min Su +3 more
semanticscholar +1 more source
Aurora B: Hooking up with cyclin-dependent kinases [PDF]
Cell Cycle, 2013 Aurora B (Aurkb) is one of the major protein kinases that ensures the proper execution and fidelity of mitosis.1 A member of the chromosomal passenger complex, Aurkb has been implicated in various mitotic functions, including chromosome-microtubule interactions, sister chromatid cohesion, the spindle-assembly checkpoint and cytokinesis.2 As it is ...
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Cyclin B targets p34cdc2 for tyrosine phosphorylation. [PDF]
The EMBO Journal, 1991 A universal intracellular factor, the 'M phase-promoting factor' (MPF), triggers the G2/M transition of the cell cycle in all organisms. In late G2, it is present as an inactive complex of tyrosine-phosphorylated p34cdc2 and unphosphorylated cyclin Bcdc13.
L, Meijer, L, Azzi, J Y, Wang
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PKM2 Interacts With the Cdk1-CyclinB Complex to Facilitate Cell Cycle Progression in Gliomas
Frontiers in Oncology, 2022 PKM2 is a phosphotyrosine-binding glycolytic enzyme upregulated in many cancers, including glioma, and contributes to tumor growth by regulating cell cycle progression. We noted, however, that in multiple glioma cell lines, PKM2 knock-down resulted in an
Shigeo Ohba +6 more
doaj +1 more source
The cell cycle–apoptosis connection revisited in the adult brain [PDF]
, 2005 Adult neurogenesis is studied in vivo using thymidine analogues such as bromodeoxyuridine (BrdU) to label DNA synthesis during the S phase of the cell cycle.
Bauer, Sylvian, Patterson, Paul H.
core +3 more sources
Haematologica, 2009 In a subset of B-cell malignancies, the genes encoding members of the cyclin D familiy are juxtaposed to immunoglobulin loci through recurrent chromosomal translocations.
Inga Nagel +9 more
doaj +1 more source
Early transformation event from follicular lymphoma: our experience of four cases
Polish Journal of Pathology, 2022 Follicular lymphoma (FL) is a mature B-cell lymphoma that can transform into a more aggressive disease such as diffuse large B-cell lymphoma, Burkitt lymphoma, or precursor B-lymphoblastic leukaemia/lymphoma. The process of transformation of FL occurs by
Anurag Mehta +2 more
doaj +1 more source
Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis [PDF]
, 2007 Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene initiate a majority of colorectal cancers. Acquisition of chromosomal instability is an early event in these tumors.
Clarke, Alan +9 more
core +5 more sources
Cell Cycle Control by Xenopus p28^(Kix1) a Developmentally Regulated Inhibitor of Cyclin-dependent Kinases [PDF]
, 1996 We have isolated Xenopus p28^(Kix1), a member of the p21^(CIP1)/p27^(KIP1)/p57^(KIP2) family of cyclin-dependent kinase (Cdk) inhibitors. Members of this family negatively regulate cell cycle progression in mammalian cells by inhibiting the activities of
Dunphy, William G., Shou, Wenying
core