Results 91 to 100 of about 63,908 (269)
Platelets, 2017 Platelet rich plasma (PRP) contains various cytokines and growth factors which may be beneficial to the healing process of injured muscle. The purpose of this study is to investigate the effect and molecular mechanism of PRP releasate on proliferation of
Wen-Chung Tsai +6 more
doaj +1 more source
Cyclin-B1: Key Player in G2 to M Phase Transition [PDF]
, 2013 poster abstractCyclins are a group of eukaryotic cellular proteins whose levels fluctuate through the course of the cell cycle. Cyclin B1 is a protein (enzyme) that is coded for by the CCNB1 gene.
Syed, Ghayasul I.
core
Cyclin D1 integrates G9a-mediated histone methylation. [PDF]
, 2019 Lysine methylation of histones and non-histone substrates by the SET domain containing protein lysine methyltransferase (KMT) G9a/EHMT2 governs transcription contributing to apoptosis, aberrant cell growth, and pluripotency.
Casimiro, Mathew C. +13 more
core +2 more sources
Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
Advanced Science, EarlyView.Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska +18 more
wiley +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov +2 more
wiley +1 more source
Nuclear Localization of Cyclin B1 Controls Mitotic Entry After DNA Damage [PDF]
, 1998 Mitosis in human cells is initiated by the protein kinase Cdc2-cyclin B1, which is activated at the end of G2 by dephosphorylation of two inhibitory residues, Thr14 and Tyr15.
Bailly +51 more
core +5 more sources
Optimization of a genetically encoded biosensor for cyclin B1-cyclin dependent kinase 1
Mol. BioSyst., 2014 Fluorescent protein (FP)-based biosensors have revolutionized the ability of researchers to monitor enzyme activities in live cells. While the basic design principles for FP-based biosensors are well established, first-generation biosensor constructs typically suffer from relatively low fluorescence responses that limit their general applicability. The
Brittney R. Sell +4 more
openaire +4 more sources
BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
Gastroenterology Research and Practice, 2009 Adenocarcinomas of rectum and colon may be different with regard to the cellular biological basis for cancer development. A material of 246 rectal cancers removed surgically at Akershus University Hospital in the years 1992–2000 was investigated and was ...
Rolf Aamodt +5 more
doaj +1 more source
The toxic effects and possible mechanisms of Brusatol on mouse oocytes. [PDF]
PLoS ONE, 2017 Brusatol is a natural quassinoid that shows a potential therapeutic use in cancer models by the inhibition of Nuclear factor erythroid 2-related factor 2 (Nrf2) and is capable of inducing a variety of biological effects. The effects of Brusatol on oocyte
Rujun Ma +6 more
doaj +1 more source