Results 111 to 120 of about 34,398 (227)

A pancancer analysis of the oncogenic role of cyclin B1 (CCNB1) in human tumors. [PDF]

Sci Rep, 2023
Dai P, Xiong L, Wei Y, Wei X, Zhou X, Zhao J, Tang H.   +6 more
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Cardioprotective effects of prolyl hydroxylase inhibitors during reperfusion in myocardial infarction: A study using cardiosphere‐derived cells

Experimental Physiology, EarlyView.
Abstract Cardiosphere‐derived cells (CDCs) are a promising in vitro model for studying myocardial ischaemia–reperfusion (I–R) injury and testing potential therapeutic interventions. This study investigated the suitability of CDCs as a model for myocardial infarction (MI) and the effects of prolyl hydroxylase inhibitor (PHI) administration during ...
Luca Salhöfer, Ulrike B. Hendgen‐Cotta, Joachim Fandrey, Timm Schreiber, Tristan Leu   +4 more
wiley   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Phyllanthus emblica Exerts Therapeutic Potential in Oral Cancer Through Multiple Pathways

eFood, Volume 7, Issue 2, April 2026.
Graphic Illustration of the Multifaceted Therapeutic Potential of PEWE, 1. Phyllanthus emblica water extract (PEWE) demonstrates potent anticancer effects against oral cancer by inhibiting cell proliferation, migration, and invasion while inducing apoptosis and autophagy. 2.
Tai‐Pei Lin, Min‐Hsiung Pan, Chan‐Hua Chang, Kuan‐Chung Hsiao, Yen‐Lin Chen, Jui‐Sheng Lai, Wen‐Chan Yang, Ann‐Joy Cheng, Yin‐Ju Chen, Chiou‐Ying Yang, Meng‐Yuan Huang, Ko‐Jiunn Liu   +11 more
wiley   +1 more source

Cyclin B1 (CCNB1) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

KCNN1 promotes proliferation and metastasis of breast cancer via ERLIN2-mediated stabilization and K63-dependent ubiquitination of Cyclin B1. [PDF]

Carcinogenesis, 2023
Xiao B, Xiang Q, Deng Z, Chen D, Wu S, Zhang Y, Liang Y, Wei S, Luo G, Li L.   +9 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, Volume 20, Issue 3, Page 688-708, March 2026.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

SETDB2 interacts with BUBR1 to induce accurate chromosome segregation independently of its histone methyltransferase activity

FEBS Open Bio
SETDB2 is a H3K9 histone methyltransferase required for accurate chromosome segregation. Its H3K9 histone methyltransferase activity was reported to be associated with chromosomes during metaphase. Here, we confirm that SETDB2 is required for mitosis and
Yanhong Tu, Haomiao Zhang, Jialin Xia, Yu Zhao, Ruifang Yang, Jing Feng, Xueyun Ma, Jing Li   +7 more
doaj   +1 more source