Results 131 to 140 of about 34,398 (227)

Emex spinosa (L.) Campd.: A Review on Ethnomedicinal, Phytochemical, Pharmacological, and Toxicological Profile

open access: yesChemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Graphical abstract illustrating the pharmacological potential of E. spinosa. ABSTRACT Emex spinosa (L.) Campd. (E. spinosa) is a plant species belonging to the Polygonaceae family. It is native to the Middle East, North Africa, and Europe and is most commonly seen on the coastlines of Mediterranean countries.
Smail Amtaghri   +9 more
wiley   +1 more source

Restricting Synaptotagmin‐3 Internalization Mitigates Cerebral Ischemia/Reperfusion Injury by Curtailed Neuronal Apoptosis and Microglial Re‐Programming

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Restriction of Syt3 internalization by peptide 3Y conferred robust neuroprotection against cerebral ischemia/reperfusion injury. Mechanistically, 3Y suppressed neuronal apoptosis fundamentally, and additionally, these salvaged neurons orchestrated and remodulated the transformation of surrounding microglia toward an anti‐inflammatory and ...
Hua Xu   +7 more
wiley   +1 more source

Targetable Vulnerabilities in MYC‐Driven B Cell Lymphomas Resistant to BCR Extinction

open access: yesHematological Oncology, Volume 44, Issue 2, March 2026.
ABSTRACT Polatuzumab vedotin, an antibody‐drug conjugate (ADC) targeting the B cell receptor (BCR) signaling subunit CD79B, has recently entered frontline therapy for diffuse large B cell lymphoma (DLBCL) and high‐grade B cell lymphoma (HGBCL), achieving encouraging clinical results. However, MYC‐driven B cell lymphomas, particularly HGBCL with MYC and
Silvia Brambillasca   +15 more
wiley   +1 more source

Cyclin B1 expression as an independent prognostic factor for lung adenocarcinoma and its potential pathways. [PDF]

open access: yesOncol Lett, 2022
Li Y   +9 more
europepmc   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, Volume 12, Issue 1, Page 96-122, Spring 2026.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Dissecting the roles of the Tuberin protein in the subcellular localization of the G2/M Cyclin, Cyclin B1. [PDF]

open access: yesPLoS One, 2022
Pillon A   +4 more
europepmc   +1 more source

From Pharmaceutical to Biophysical Therapies: New Horizons in Inflammatory Bowel Disease Management

open access: yesJCC Plus, Volume 1, Issue 2, March 2026.
Important limitations exist in the current pharmacological landscape of Inflammatory Bowel Disease (IBD), such as variable response rates and treatment‐limiting adverse effects. In this review, we perform a critical assessment of the current literature on novel multimodal biophysical approaches showing alternative mechanisms of action to, and potential
Benedetta Ricchi   +7 more
wiley   +1 more source

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