Results 71 to 80 of about 67,241 (220)
Cell Cycle-dependent Regulation of the Cyclin B1 Promoter [PDF]
Journal of Biological Chemistry, 1995 Cyclin B1 mRNA expression varies through the cell cycle with its peak in G2/M. In cycling mammalian cells, its lowest level is in G1 with a steady increase in S until a level 50-fold greater than that in G1 is reached. In order to characterize the transcriptional component to this variation in expression, we cloned the upstream region 872 base pairs ...
A, Hwang +3 more
openaire +2 more sources
miR-379 regulates cyclin B1 expression and is decreased in breast cancer. [PDF]
PLoS ONE, 2013 MicroRNAs are small non-coding RNA molecules that control gene expression post-transcriptionally, and are known to be altered in many diseases including breast cancer. The aim of this study was to determine the relevance of miR-379 in breast cancer.
Sonja Khan +9 more
doaj +1 more source
Cyclin B1/CDK1-regulated mitochondrial bioenergetics in cell cycle progression and tumor resistance. [PDF]
, 2019 A mammalian cell houses two genomes located separately in the nucleus and mitochondria. During evolution, communications and adaptations between these two genomes occur extensively to achieve and sustain homeostasis for cellular functions and ...
Jiang, Nian +3 more
core
Securin Is Not Required for Chromosomal Stability in Human Cells [PDF]
, 2005 Abnormalities of chromosome number are frequently observed in cancers. The mechanisms regulating chromosome segregation in human cells are therefore of great interest.
Azofeifa +32 more
core +4 more sources
Analytical Cellular Pathology, 2018 We analysed the expression of cyclins A2, B1, D1, and E1 by immunohistochemistry and numerical aberrations in CCND1 gene by fluorescence in situ hybridization technique in 67 primary oral squamous cell carcinomas (OSCC). Cyclin A2 expression was observed
Luís Silva Monteiro +5 more
doaj +1 more source
Nrf2 is essential for timely M phase entry of replicating hepatocytes during liver regeneration [PDF]
, 2015 The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) regulates various cellular activities, including redox balance, detoxification, metabolism, autophagy, proliferation, and apoptosis.
Bao, Qi +7 more
core +1 more source
Cyclin B1 and Other Cyclins as Tumor Antigens in Immunosurveillance and Immunotherapy of Cancer [PDF]
Cancer Research, 2006 Abstract Uncontrolled cell division is an indispensable event in tumor progression, and numerous molecules involved in this process have been the focus of intense investigation in tumor biology. Cyclins, molecules that orchestrate normal cell cycle progression, are abnormally overexpressed in various human cancers.
Ann Marie, Egloff +2 more
openaire +2 more sources
USP39-mediated deubiquitination of Cyclin B1 at Lys242 promotes tumor cell cycle G2/M transition and glioma progression [PDF]
, 2022 Weilin Chen +8 more
openalex +1 more source
Cyclin-B1: Key Player in G2 to M Phase Transition [PDF]
, 2013 poster abstractCyclins are a group of eukaryotic cellular proteins whose levels fluctuate through the course of the cell cycle. Cyclin B1 is a protein (enzyme) that is coded for by the CCNB1 gene.
Syed, Ghayasul I.
core
Platelets, 2017 Platelet rich plasma (PRP) contains various cytokines and growth factors which may be beneficial to the healing process of injured muscle. The purpose of this study is to investigate the effect and molecular mechanism of PRP releasate on proliferation of
Wen-Chung Tsai +6 more
doaj +1 more source