Runt-related transcription factor 1 (RUNX1; AML1); runt-related transcription factor 1 translocated to 1 (cyclin D-related) (RUNX1T1; ETO) [PDF]
Shuo Dong
openalex +1 more source
Cycling Quiescence in Temozolomide Resistant Glioblastoma Cells Is Partly Explained by microRNA-93 and -193-Mediated Decrease of Cyclin D. [PDF]
Munoz JL+6 more
europepmc +1 more source
Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase [PDF]
Cascales, H.S.+4 more
core +3 more sources
A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway [PDF]
Xinliang Mao+16 more
openalex +1 more source
ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner. [PDF]
Suk FM+6 more
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Targeting Cyclin D-CDK4/6 Sensitizes Immune-Refractory Cancer by Blocking the SCP3-NANOG Axis. [PDF]
Oh SJ+16 more
europepmc +1 more source
Navigating the treatment landscape of Alzheimer's disease: Current strategies and future directions
Alzheimer's disease treatment is evolving rapidly, with emerging strategies targeting multiple disease pathways. This graphical abstract highlights the shift from traditional therapies to innovative approaches that hold promise for improving outcomes.
Tapas Kumar Mohapatra+4 more
wiley +1 more source
Ras signals principally via Erk in G1 but cooperates with PI3K/Akt for Cyclin D induction and S-phase entry. [PDF]
Vasjari L+4 more
europepmc +1 more source