Results 71 to 80 of about 584,094 (211)
Defining the residues governing the mitotic destruction of Drosophila cyclin A [PDF]
Mitotic destruction of cyclin A has remained enigmatic ever since it was discovered. Regulation of cyclin A proteolysis appears to be different from that of other mitotic cyclins in diverse species.
Ramachandran, Vimal
core
Prediction of repurposed drugs for treating lung injury in COVID-19 [PDF]
Coronavirus disease (COVID-19) is an infectious disease discovered in 2019 and currently in outbreak across the world. Lung injury with severe respiratory failure is the leading cause of death in COVID-19, brought by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
arxiv
Using Genomics to Identify High-Risk Myeloma after Autologous Stem Cell Transplantation [PDF]
Multiple myeloma is a malignancy of antibody-secreting plasma cells that expand in the bone marrow. Although high-dose therapy/autologous stem cell transplantation has become the standard of care for patients with multiple myeloma, survival is highly ...
Barlogie, Bart, Shaughnessy, John D.
core +1 more source
Periodic higher rank graphs revisited [PDF]
Let $P$ be a finitely generated cancellative abelian monoid. A $P$-graph $\Lambda$ is a natural generalization of a higher rank graph. A pullback of $\Lambda$ is constructed by pulling it back over a given monoid morphism to $P$, while a pushout of $\Lambda$ is obtained by modding out its periodicity $\Per\Lambda$, which is deduced from a natural ...
arxiv
Cell cyclins: triggering elements of cancer or not? [PDF]
Cyclins are indispensable elements of the cell cycle and derangement of their function can lead to cancer formation. Recent studies have also revealed more mechanisms through which cyclins can express their oncogenic potential. This review focuses on the
A Koff+60 more
core +3 more sources
Bifurcation in cell cycle dynamics regulated by p53 [PDF]
We study the regulating mechanism of p53 on the properties of cell cycle dynamics in the light of the proposed model of interacting p53 and cell cycle networks via p53. Irradiation (IR) introduce to p53 compel p53 dynamics to suffer different phases, namely oscillating and oscillation death (stabilized) phases.
arxiv
The Italian bondage and reinforcement numbers of digraphs [PDF]
An \textit{Italian dominating function} on a digraph $D$ with vertex set $V(D)$ is defined as a function $f : V(D) \rightarrow \{0, 1, 2\}$ such that every vertex $v \in V(D)$ with $f(v) = 0$ has at least two in-neighbors assigned $1$ under $f$ or one in-neighbor $w$ with $f(w) = 2$.
arxiv
Cyclin D-CDK4 Disulfide Bond Attenuates Pulmonary Vascular Cell Proliferation. [PDF]
Knight H+13 more
europepmc +1 more source
Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro [PDF]
Initiation of mammalian DNA replication can be reconstituted from isolated G1-phase nuclei and cell extracts, supplemented with cyclin-dependent protein kinases (CDKs).
Ainscough+30 more
core +3 more sources
Expression analysis of cyclin D, Ki-67, MCM3 and MCM2 in oral squamous cell carcinoma. [PDF]
Vala D+5 more
europepmc +1 more source