Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy. [PDF]
NPJ Breast Cancer, 2022 Gharbi SI +22 more
europepmc +1 more source
Cell Cycle Analysis of Atrazine-Treated Human Cells [PDF]
, 2008 Atrazine is the second most-commonly applied herbicide in the United States. Studies have correlated herbicide exposure with a variety of health risks in non-target organisms, including humans and amphibians.
Pelzer, Daniel
core +1 more source
Author Correction: Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy. [PDF]
NPJ Breast Cancer, 2022 Gharbi SI +22 more
europepmc +1 more source
Complex Systems Analysis of Cell Cycling Models in Carcinogenesis [PDF]
arXiv, 2004 Carcinogenesis is a complex process that involves dynamically inter-connected modular sub-networks that evolve under the influence of micro-environmentally induced perturbations, in non-random, pseudo-Markov chain processes. An appropriate n-stage model of carcinogenesis involves therefore n-valued Logic treatments of nonlinear dynamic transformations ...
arxiv
Cyclin D1 integrates G9a-mediated histone methylation. [PDF]
, 2019 Lysine methylation of histones and non-histone substrates by the SET domain containing protein lysine methyltransferase (KMT) G9a/EHMT2 governs transcription contributing to apoptosis, aberrant cell growth, and pluripotency.
Casimiro, Mathew C. +13 more
core +2 more sources
Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase. [PDF]
, 1994 Jun‐ya Kato +3 more
openalex +1 more source
Expression of p53, p63, p16, Ki67, Cyclin D, Bcl-2, and CD31 Markers in Actinic Keratosis, In Situ Squamous Cell Carcinoma and Normal Sun-Exposed Skin of Elderly Patients. [PDF]
J Clin Med, 2023 Balcere A +6 more
europepmc +1 more source
Tumourigenic and tumour suppresive properties of KSHV cyclin in vitro and in vivo [PDF]
, 2003 Expression of the Kaposi's sarcoma-associated herpesvirus (KSHV or HHV-8) cyclin D homologue, K cyclin, may contribute to viral oncogenesis. This thesis shows that ectopic expression of K cyclin also triggers an apoptotic response.
Verschuren, Emma Wilhelmina
core
Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer [PDF]
, 2003 p27 is a key regulator of progression from G1 to S phase. Although the gene encoding p27 is rarely mutated in human cancers, p27 is functionally inactivated in a majority of human cancers through accelerated p27 proteolysis, through sequestration by ...
Alkarain, Angel, Slingerland, Joyce
core +2 more sources
D-type cyclin-dependent kinase activity in mammalian cells. [PDF]
, 1994 H Matsushime +5 more
openalex +1 more source