Results 181 to 190 of about 96,425 (243)

Cyclin D1 expression in penile cancer. [PDF]

Oncotarget
Duarte WE, Pinho JD, Melo SPDC, Duarte DRD, Carmo JMDGRD, Khayat AS, Calixto JRR, Campos MAG, Correa RDGCF, Júnior AMA, Teixeira-Júnior AAL, Silva GEB.   +11 more
europepmc   +1 more source

Synthesis of quinolinyl/isoquinolinyl[a]pyrrolo [3,4-c] carbazoles as cyclin D1/CDK4 inhibitors

, 2003
Guoxin Zhu, Scott E. Conner, Xun Zhou, Chuan Shih, Harold B. Brooks, Eileen L. Considine, Jack Dempsey, Cathy Ogg, Bharvin Patel, Richard M. Schultz, Charles D. Spencer, Beverly A. Teicher, Scott A. Watkins   +12 more
openalex   +1 more source

HMGB2 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through MTA2‐Driven Metabolic Reprogramming

Advanced Science, Volume 13, Issue 1, 5 January 2026.
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou, Ling‐Feng Gu, Yi‐Xi Chen, Peng Jing, Tong‐Tong Yang, Ye He, Yu‐Lin Bao, Xiang‐Zheng Zhang, Chong Du, Si‐Bo Wang, Tian‐Kai Shan, Jia‐Yi Chen, Hao Wang, Qi‐Ming Wang, Li‐Ping Xie, Yang Zhao, Yong Ji, Lian‐Sheng Wang   +17 more
wiley   +1 more source

Deciphering the effects of bixin on pulmonary alveolar adenocarcinoma migration and proliferation via targeting BAX/BCL-2 and Cyclin D1. [PDF]

Sci Rep
Varghese R, Ramamoorthy S.
europepmc   +1 more source

EM2, a Natural Product MST1/2 Kinase Activator, Suppresses Non‐Small Cell Lung Cancer via Hippo Pathway Activation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
EM2 directly binds to and activates MST1/2, enhancing their kinase activity and sequentially promoting LATS phosphorylation, which increases YAP phosphorylation. Consequently, YAP nuclear translocation is suppressed, leading to reduced transcription of downstream targets CTGF and CYR61, ultimately exerting a robust inhibitory effect on NSCLC cell ...
Siyu Yang, Huayan Xie, Qiang Lin, Liujin Zhou, Junxi Liu, Zekai Fang, Ziling Tang, Ruijie Yuan, Jinxuan Su, Sijia Li, Wenlin Wang, Mingyu Pan, Hao Wang, Xiaoyong Dai, Guocai Wang, Yubo Zhang   +15 more
wiley   +1 more source

Assessment of Cyclin D1 Expression: Prognostic Value and Functional Insights in Endometrial Cancer: In Silico Study. [PDF]

Int J Mol Sci
Szymański M, Jerka D, Bonowicz K, Antosik P, Gagat M.   +4 more
europepmc   +1 more source

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source

In Situ Assembly of Transformable Monopeptide on Activated Neutrophils Attenuates NETs‐Induced Hepatocellular Carcinoma Metastasis by Disrupting NE Nuclear Translocation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Activated neutrophils release extracellular traps (NETs) that promote tumor metastasis. FTP‐NPs are develpoed, a peptidic nanomaterial that binds NE on neutrophil membranes, forming NE‐fibril clusters that deactivate NE and prevent NETs formation. This strategy reduces metastasis and enhances the anti‐tumor immune response by targeting NE subcellular ...
Yichi Chen, Yijun Wang, Haitao Shang, Jiayue Qiu, Ruotian Zhang, Yuxiang Xiong, Tong Wang, Fengyi Wang, Anbang Wu, Xin Lin, Bolin Wu, Chen Huang, Wen Cheng, Lu Zhang   +13 more
wiley   +1 more source

MiR-146b overexpression promotes bladder cancer cell growth via the SMAD4/C-MYC/Cyclin D1 axis. [PDF]

Front Oncol
Zhu J, Zheng Z, Yin Z, Ding L, Li C, Wang X, Shu P, Zhou J, Liu W, Liu J.   +9 more
europepmc   +1 more source

Ara-c induces cell cycle G1/S arrest by inducing upregulation of the INK4 family gene or directly inhibiting the formation of the cell cycle-dependent complex CDK4/cyclin D1

, 2019
Fuze Sun, Niannian Li, Xiaoling Tong, Jie Zeng, Songzhen He, Tingting Gai, Yanmin Bai, Lanlan Liu, Kunpeng Lu, Jianghong Shen, Minjin Han, Cheng Lü, Fangyin Dai   +12 more
openalex   +1 more source