Results 161 to 170 of about 299,961 (316)
The Journal of Pathology, EarlyView.Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi +8 more
wiley +1 more source
Transizyonel hücreli mesane kanserinde cyclin-D1 proto-onkojen ekspresyonu [PDF]
, 1999 Öz: Bu çalışmada yüzeyel mesane kanserlerinde hücre-siklus düzenleyici proteinlerden cyclin-D1 onkoprotein ekpresyonunu ve bunun tümör greydi ile ilişkisi araştırıldı. Çalışmaya 45 mesane kanserli hastaya ait parafinize tümör dokusu alındı.
Mızrak, Bülent +5 more
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Specific transformation abolishes cyclin D1 fluctuation throughout the cell cycle [PDF]
, 1996 We analysed cyclin D1 mRNA and protein expression in several different cell types after separating these cells according to their different cell cycle phases by centrifugal elutriation.
Hengstschläger, Markus +11 more
core +1 more source
Biology of Sex Differences, 2011 Background Although colorectal cancer (CRC) is generally not considered to be a hormone-dependent malignancy, several sex-related differences in incidence, molecular characteristics and survival have been reported.
Wangefjord Sakarias +5 more
doaj +1 more source
Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives
Precision Medical Sciences, EarlyView.Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley +1 more source
jumonji Downregulates Cardiac Cell Proliferation by Repressing cyclin D1 Expression [PDF]
, 2003 Spatiotemporal regulation of cell proliferation is necessary for normal tissue development. The molecular mechanisms, especially the signaling pathways controlling the cell cycle machinery, remain largely unknown.
Kojima, Mizuyo +9 more
core +1 more source
Unusual Cutaneous and Lymphatic Findings in an Adult Patient
JEADV Clinical Practice, EarlyView.
Sarah Preis +4 more
wiley +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Regulation of cyclin D1 gene expression [PDF]
Cyclin D1 is a key regulator of cell proliferation and its expression is subject to both transcriptional and post-transcriptional regulation. in different cellular contexts, different pathways assume a dominant role in regulating its expression, whereas ...
Witzel II, Koh LF, Perkins ND
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