Results 181 to 190 of about 154,360 (283)

LL‐37: Biological Mechanisms and Emerging Therapeutic Applications in Intestinal Disease

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Human cathelicidin peptide LL‐37 is encoded by the CAMP gene and plays a key role in innate immunity. It maintains intestinal homeostasis through antibacterial, immunomodulation, and tissue repair functions. This paper reviews the multiple functions of LL‐37 in the intestinal‐immune axis and its contribution to intestinal immune homeostasis. A
Qichao Liu, Peng Xu, Cheng Zhang
wiley   +1 more source

BMX inhibition overcomes small cell lung cancer chemoresistance by stabilizing E2F1 via ERK1/2-Cyclin D1/CDK4/6 axis. [PDF]

Signal Transduct Target Ther
Wu T, Qi S, Shi C, Wu C, Liu Q, Hu C, Hu J, Wang A, Liu J, Qi Z, Wang W, Liu Q.   +11 more
europepmc   +1 more source

Impact of organic pollutants on phenotype and gene expression in human breast cancer cells

Journal of Applied Toxicology, Volume 46, Issue 5, Page 1487-1505, May 2026.
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin, Heloisa Amancio, Jessica Zablocki da Luz, Aliciane de Almeida Roque, Tugstênio Lima de Souza, José Eduardo Vargas, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto   +7 more
wiley   +1 more source

Expression of Cyclin D1, p53, and Tumor-Associated Tissue Eosinophils in Different Grades of Oral Squamous Cell Carcinoma. [PDF]

Cureus
Habib M, Rauf M, Omair S, Chaudry SS, Khan AR, Ahmad A, Sheikh A.   +6 more
europepmc   +1 more source

When Viruses Talk through Extracellular Vesicles: a New Perspective on Sars‐Cov‐2‐Induced Neurodegeneration

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT SARS‐CoV‐2 infection is linked to persistent neurological symptoms Post‐Acute Sequelae SARS‐CoV‐2 (neuro‐PASC) and elevated risk of neurodegenerative disease, but molecular events connecting acute viral injury to long‐term CNS dysfunction remain unclear.
Gunjan Bawne, Loet Coenen, Erik Nutma, Jinte Middeldorp, Magdalena J. Lorenowicz   +4 more
wiley   +1 more source

Expression of Concern: Regulation of Glioblastoma Progression by Cord Blood Stem Cells Is Mediated by Downregulation of Cyclin D1. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Case series: Joubert syndrome and eosinophilic esophagitis

JPGN Reports, Volume 7, Issue 2, Page 329-331, May 2026.
Abstract Joubert syndrome (JS) is a rare genetic disorder characterized by developmental abnormalities, particularly in the brainstem and cerebellar vermis, alongside multisystem manifestations such as kidney and liver anomalies, polydactyly, cleft lip or palate, and tongue defects.
Jonathon Schening, Stephanie Leon‐Paredes, Eric Chiou, Vibha Szafron, Anthony Olive, Sara Anvari   +5 more
wiley   +1 more source

Elevated SNHG15 empowers keratinocytes hyperproliferation through activation of STAT3/Cyclin D1 axis in psoriasis. [PDF]

Acta Pharm Sin B
Tang L, Li G, Chang J, Xian H, Liu Y, Lin L, Dai Z, Liu Z, Qiu X, Zhang B, Su Z, Feng B, Zhu Y, Wang M, Chen Y, Liu H, Wu D, Li C, Zhao J, Li M, Zhu Y, Xie X, Deng H, Ye S, Fan S, Bi H, Lu C, Zheng G.   +27 more
europepmc   +1 more source

Liver Stiffness Characterization of OGTLKO Mouse Model of Progressive Liver Fibrosis

Journal of Ultrasound in Medicine, Volume 45, Issue 5, Page 1069-1082, May 2026.
Objectives O‐GlcNAcylation plays a key regulatory role in hepatic physiology, and its disruption leads to fibrosis in liver‐specific OGT knockout mice (OGTLKO), making this model valuable for studying advanced metabolic dysfunction‐associated steatohepatitis (MASH).
Gilles Renault, Lenin Chinchilla, Lourdes Massengo, Pierre Monbernard, Fadila Benhamed, Marion Regnier, Raphael Denis, Catherine Postic, Anthony Novell, Jean‐Luc Gennisson   +9 more
wiley   +1 more source

[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells <i>in vitro</i> and affects expression of cyclin D1 and MMP‑9. [PDF]

Oncol Rep
Yuan Z, Sanders AJ, Ye L, Wang Y, Jiang WG.   +4 more
europepmc   +1 more source