Results 151 to 160 of about 259,083 (282)

ICSH Guidance on Bone Marrow Examination and Reporting

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber   +6 more
wiley   +1 more source

Rate-limiting Effects of Cyclin D1 in Transformation by ErbB2 Predicts Synergy between Herceptin and Flavopiridol.

open access: yes, 2002
Cyclin D1 is downstream of erbB2 and is required for erbB2 transformation. Here we report thatcyclin D1 functions are essential, rate limiting for erbB2 transformation, and reciprocally increase erbB2 levels.
Kempkes, B.   +3 more
core  

C‐type cyclin CycC1;1 delays leaf senescence by interacting with and inhibiting MYC2 in Arabidopsis

open access: yesJournal of Integrative Plant Biology, EarlyView.
The C‐type cyclin CycC1;1 interacts with MYC2 and MED25 to block their association and RNA polymerase II recruitment, thereby repressing senescence‐associated gene expression and delaying leaf senescence in Arabidopsis. Unlike jasmonic acid‐inducible JAZ repressors, CycC1;1 operates independently of jasmonic acid signaling, representing an ...
Cai‐Yi Liao   +9 more
wiley   +1 more source

Effects of N‐Acetylcysteine on Oxidative Status and Intestinal Health in Piglets (Sus scrofa domesticus L.): A PRISMA‐Based Systematic Review

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Oxidative stress is a critical challenge in intensive swine production, particularly during weaning, compromising intestinal integrity and animal performance. N‐acetylcysteine (NAC) has emerged as a multifunctional nutritional strategy to mitigate these effects due to its role as a glutathione precursor and signaling modulator. This systematic
Jessica Lucilene Cantarini Buchini   +7 more
wiley   +1 more source

The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?

open access: yesJournal of Periodontal Research, EarlyView.
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander   +3 more
wiley   +1 more source

GLP‐1 Receptor Agonists and Cancer Risk in Obesity Treatment

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is a well‐established risk factor for numerous cancers, with body habitus, especially central adiposity, contributing to increased cancer incidence and worse prognosis. Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs), initially developed to treat Type 2 diabetes, have rapidly gained prominence as powerful anti‐obesity agents due ...
Lorne J. Hofseth   +6 more
wiley   +1 more source

Aberrant Accumulation of Cyclin D1 Rewires Glutamine Metabolism and Generates a Metabolic Vulnerability in Squamous Cell Carcinoma. [PDF]

open access: yesCancer Res
Zhang S   +11 more
europepmc   +1 more source

Molecular Links Between Heat Stress and DNA Damage Response in Plants

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Climate change poses a major threat to agricultural productivity and, consequently, to global food security. Among the consequences of climate change, heat stress (HS) has emerged as a critical factor limiting crop performance. This has stimulated extensive research over the past decade to elucidate the molecular and physiological mechanisms ...
Adrian Calves‐Ubach   +1 more
wiley   +1 more source

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