A small deletion in the 3′-untranslated region of the cyclin D1/PRAD1/bcl-1 oncogene in a patient with chronic lymphocytic leukemia [PDF]
Yoshitaka Hosokawa+7 more
openalex +1 more source
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal+3 more
wiley +1 more source
TGF-?-1 up-regulates cyclin D1 expression in colo-357 cells, whereas suppression of cyclin d1 levels is associated with down-regulation of the type I TGF-? receptor [PDF]
Marko Kornmann+2 more
openalex +1 more source
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye+5 more
wiley +1 more source
Inhibition of Cyclin D1 Expression and Induction of Apoptosis by Inostamycin in Small Cell Lung Carcinoma Cells [PDF]
Masaya Imoto+5 more
openalex +1 more source
Uterine Mesenchymal Neoplasm With a Novel CDC42::PLAG1 Fusion
PLAG1 rearranged uterine mesenchymal neoplasms.
Pranav Dorwal+4 more
wiley +1 more source
Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer. [PDF]
Shirole NH+15 more
europepmc +1 more source
Cyclin D1 and retinoblastoma susceptibility gene alterations in non‐small cell lung cancer [PDF]
Antonio Marchetti+11 more
openalex +1 more source
Elevated cortisol concentration in preterm sheep fetuses impacts heart development
Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi+9 more
wiley +1 more source