Results 211 to 220 of about 154,360 (283)

SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley   +1 more source

MiR-145-5p arrests the cell cycle by modulating SMAD5/cyclin D1 to inhibit gastric cancer progression. [PDF]

Front Cell Dev Biol
Wang L, Guo J, Lv C, Kong L, Cui J, Wang Z, Guo Y, Jia R, Guan T, Yu B, Li F.   +10 more
europepmc   +1 more source

Testosterone Exposure During Fetal Masculinization Programming Window Determines the Kidney Size in Adult Mice

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Kidney size is sex‐dimorphic and regulated by androgens in adult humans and mice. Male mice lacking the main testosterone‐producing enzyme HSD17B3 had reduced testosterone during a short fetal time window, leading to reduced size of kidneys in adults, which were not responsive to high adult testosterone.
Arttu Junnila, Kalle T. Rytkönen, Guillermo Martinez‐Nieto, Mats Perk, Otto Mäkelä, Hao Li, Jenni Airaksinen, Ida Hyötyläinen, Oliver Mehtovuori, Asta Laiho, Claes Ohlsson, Laura L. Elo, Satu Kuure, Matti Poutanen, Petra Sipilä   +14 more
wiley   +1 more source

The Roles of PD-L1, Ki-67, P53, and Cyclin D1 in PitNETs: Diagnostic and Prognostic Implications in a Series of 74 Patients. [PDF]

Int J Mol Sci
Krzentowska A, Biesaga B, Czepko R, Merklinger-Gruchała A, Adamek D, Jasińska M, Pluta B, Michalska W, Wróblewska K, Janczy F, Gołkowski F.   +10 more
europepmc   +1 more source

TFE3 fusion proteins promoted the progression of Xp11.2 translocation renal cell carcinoma through post-translational modification of PDL1 by upregulating CCND1/Cyclin D1. [PDF]

Cell Oncol (Dordr)
Lu Y, Chen Y, Pan X, Ma W, Liu N, Yang L, Dong X, Guo H, Li D, Gan W.   +9 more
europepmc   +1 more source

The evaluation of cyclin D1 expression in prostate carcinoma cases. [PDF]

North Clin Istanb
Aksoy A, Vicdanli S, Artas G.
europepmc   +1 more source

ANKHD1 promotes pathogenic proliferation in Autosomal Dominant Polycystic Kidney Disease via the Cyclin D1/CDK4 pathway. [PDF]

J Transl Med
Terzenidou ME, Patera F, Macleod FM, Ong ACM, Fragiadaki M.   +4 more
europepmc   +1 more source

RBBP4 downregulation increases the sensitivity of A549 and HeLa cells to cisplatin by inhibiting cyclin D1 expression. [PDF]

Clinics (Sao Paulo)
Zeng Z, Mai M, Wang D, Ouyang J, Chen Z, Zhong J, Rao J.   +6 more
europepmc   +1 more source

Deciphering the effects of bixin on pulmonary alveolar adenocarcinoma migration and proliferation via targeting BAX/BCL-2 and Cyclin D1. [PDF]

Sci Rep
Varghese R, Ramamoorthy S.
europepmc   +1 more source

Assessment of Cyclin D1 Expression: Prognostic Value and Functional Insights in Endometrial Cancer: In Silico Study. [PDF]

Int J Mol Sci
Szymański M, Jerka D, Bonowicz K, Antosik P, Gagat M.   +4 more
europepmc   +1 more source