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SHP2 inhibition and adjuvant therapy synergistically target KIT-mutant GISTs via ERK1/2-regulated GSK3β/cyclin D1 pathway. [PDF]
He C +9 more
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Simultaneous cyclin D1 overexpression and p27<sup>kip1</sup> knockdown enable robust Müller glia cell cycle reactivation in uninjured mouse retina. [PDF]
Wu Z +6 more
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PC4: A new regulator of cyclin D1 transcript levels. [PDF]
Fassl A, Sicinski P.
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Scoparone suppresses proliferation and cell cycle of hepatocellular carcinoma cells via inhibiting AKT/GSK-3β/cyclin D1 signaling pathway. [PDF]
Hong M +8 more
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Increased SOX10, p16, and Cyclin D1 Immunoreactivity Differentiates MAP Kinase-activated Low-grade Gliomas From Piloid Gliosis. [PDF]
Tang V +10 more
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Breast Cancer Research and Treatment, 1998
Cyclin D1 protein plays an important part in regulating the progress of the cell during the G1 phase of the cell cycle. The cyclin D1 gene, CCND1, is amplified in approximately 20% of mammary carcinomas, and the protein is over-expressed in approximately 50% of cases. This has led to intensive study to ascertain whether cyclin D1 is a biological marker
D M, Barnes, C E, Gillett
openaire +2 more sources
Cyclin D1 protein plays an important part in regulating the progress of the cell during the G1 phase of the cell cycle. The cyclin D1 gene, CCND1, is amplified in approximately 20% of mammary carcinomas, and the protein is over-expressed in approximately 50% of cases. This has led to intensive study to ascertain whether cyclin D1 is a biological marker
D M, Barnes, C E, Gillett
openaire +2 more sources
Cyclin D1 expression in gliomas
Acta Neuropathologica, 1998Cyclin D1 (cycD1) expression was defined immunohistochemically using monoclonal antibody DCS-6 and polyclonal antiserum H-295 in 50 glioma biopsies. The number of positive nuclei was higher for H-295 than for DCS-6, with a ratio of 3:1. The labelling index (LI) was compared to the grade of histological malignancy and to Ki-67 MIB-1 LI. The LI for cycD1
CAVALLA P +5 more
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