Results 221 to 230 of about 259,083 (282)

Histone Modifications at the Intersection of Aging, Neuroinflammation and Metabolism in Alzheimer's Disease

open access: yesAging Cell, Volume 25, Issue 11, November 2026.
This review examines how histone modifications integrate aging, metabolic dysfunction and neuroinflammation to shape persistent, cell‐type‐specific chromatin states in Alzheimer's disease. By distinguishing causal regulation from association through perturbation, persistence and reversibility, it highlights metabolic–epigenetic feedback loops and ...
Junyi Liang   +7 more
wiley   +1 more source

Study of Cyclin D1 Expression in Squamous Cell Carcinoma of Oral Cavity. [PDF]

open access: yesIndian J Otolaryngol Head Neck Surg
Parvez A   +4 more
europepmc   +1 more source

tRNA‐Derived Small RNAs in Digestive Cancers: From Translational Regulation to Immune and Extracellular Communication

open access: yesCancer Science, Volume 117, Issue 11, Page 2924-2937, November 2026.
tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley   +1 more source

Overcoming venetoclax resistance through heme-mediated NOXA/cyclin D1/Mcl-1 axis with a novel artemisinin conjugate. [PDF]

open access: yesBlood Adv
Zhang J   +13 more
europepmc   +1 more source

AKT Phosphorylation of FOXK2 at Ser398 Impacts Breast Cancer Cell Growth and Viability

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Higher FOXK2 protein levels are associated with increased AKT phosphorylation and chemoresistance in breast cancer cells. AKT modulates FOXK2 protein levels, with no such regulation in FOXK2 mRNA levels. GSK3β, a known substrate of AKT (dotted arrow), does not regulate FOXK2 in our cellular model.
L. T. Carneiro   +10 more
wiley   +1 more source

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