Results 211 to 220 of about 96,425 (243)

Circular RNAs in Diabetic Foot Ulcers: A Scoping Review of Clinical, Preclinical, and In Silico Evidence on Diagnostic and Therapeutic Potentials

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
This figure summarises circRNAs identified as therapeutic or pathogenic targets in animal models of diabetic foot ulcers. Protective circRNAs delivered via exosomes, hypoxia‐preconditioned exosomes, or lipid nanoparticles promote angiogenesis, autophagy, and oxidative stress resistance. In contrast, silencing of pathogenic circRNAs such as circ_0005654
Amir Reza Ghafourian, Masoomeh Hamdi, Atefeh Soltan Mohseni, Maryam Davoudi, Hamid Choobineh, Fariba Nabatchian, Reza Afrisham   +6 more
wiley   +1 more source

Simultaneous cyclin D1 overexpression and p27^kip1 knockdown enable robust Müller glia cell cycle reactivation in uninjured mouse retina. [PDF]

Elife
Wu Z, Liao B, Ying J, Keung J, Zheng Z, Ahola V, Xiong W.   +6 more
europepmc   +1 more source

Association between cyclin D1 G870A polymorphism and hepatocellular carcinoma risk: a meta-analysis

, 2016
Luo T, J Chen, Liu Jj, Huijun Li, You XM, Wang HL, Zhu SL, Li LQ   +7 more
openalex   +1 more source

MicroRNA-494 inhibits nerve growth factor-induced cell proliferation by targeting cyclin D1 in human corneal epithelial cells

, 2017
Dan Wu, Tingting Qian, Jiaxu Hong, Gang Li, Weiyun Shi, Jianjiang Xu   +5 more
openalex   +2 more sources

Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy

Food Frontiers, Volume 7, Issue 1, January 2026.
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli, Anna Maria Posadino, Roberta Giordo, Antonio Barberis, Ylenia Spissu, Redouane Lemoui, William N. Setzer, Javad Sharifi‐Rad, Gianfranco Pintus   +8 more
wiley   +1 more source

Clinical significance of Cyclin D1 by complete quantification detection in mantle cell lymphoma: positive indicator in prognosis. [PDF]

Diagn Pathol
Yang Y, Song L, Yin Y, Gao Y, Wang Y, Wu S, Wang J, Pan Y, Sui X, Jiang L, Zhang Y, Yu G.   +11 more
europepmc   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

SHP2 inhibition and adjuvant therapy synergistically target KIT-mutant GISTs via ERK1/2-regulated GSK3β/cyclin D1 pathway. [PDF]

Clin Transl Med
He C, Yu J, Mao S, Yang S, Jiang X, Huang L, Li M, He Y, Zhang X, Xiang X.   +9 more
europepmc   +1 more source

Natural Dietary Compounds Targeting NF‐κB Signaling in Cancer: Implications for Nutrition‐Based Prevention and Therapy

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Dysregulation of the nuclear factor kappa B (NF‐κB) signaling pathway is closely associated with inflammation‐driven carcinogenesis, tumor progression and resistance to conventional therapies. Sustained NF‐κB activation enhances malignant cell survival, proliferation and immune evasion by promoting proinflammatory and antiapoptotic gene ...
Maria Sharif, Iqra Mutiullah, Kafila Kausar, Rashid Khan, Muhammad Irfan, Solomon Habtemariam, Khushbukhat Khan, Cristina Quispe, William C. Cho, Javad Sharifi‐Rad, Daniela Calina   +10 more
wiley   +1 more source