Results 221 to 230 of about 152,964 (318)

Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes. [PDF]

open access: yesJ Biol Chem, 2023
Wu H   +9 more
europepmc   +1 more source

A Developmentally Regulated Switch Directs Regenerative Growth of Schwann Cells through Cyclin D1 [PDF]

open access: bronze, 2000
Haesun A. Kim   +7 more
openalex   +1 more source

MS275 Inhibits Neuroblastoma Cell Growth by Mediating H3K27ac/PROX1 Axis In Silico and In Vitro

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
Our study demonstrates that MS275, a selective HDAC inhibitor, suppresses HDAC1/3 protein expression, leading to hyperacetylation of histone H3 at lysine 27 (H3K27ac) within the PROX1 promoter region (−608 to −508). This epigenetic modification upregulates PROX1 transcription, which subsequently modulates key cellular processes, including cell cycle ...
Chao Yuan   +11 more
wiley   +1 more source

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 17, July 4, 2025.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang   +10 more
wiley   +1 more source

Prognostic significance of cyclin D1 protein levels in early-stage larynx cancer treated with primary radiation [PDF]

open access: bronze, 2000
Simon Yoo   +7 more
openalex   +1 more source

Disintegration of the KITENIN/ErbB4 Functional Complex by the Flavonoid Hispidulin Suppresses Colorectal Cancer Progression

open access: yesAdvanced Therapeutics, Volume 8, Issue 7, July 2025.
Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı   +7 more
wiley   +1 more source

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