Scoparone suppresses proliferation and cell cycle of hepatocellular carcinoma cells via inhibiting AKT/GSK-3β/cyclin D1 signaling pathway. [PDF]
Hong M +8 more
europepmc +1 more source
Biological activities, health benefits and structures of equol and its derivatives. ABSTRACT Equol is a metabolite transformed from daidzein by intestinal microorganisms and has received extensive attention due to its various pharmacological activities and therapeutic potential.
Jiao‐Jiao Zhuo +2 more
wiley +1 more source
PC4: A new regulator of cyclin D1 transcript levels. [PDF]
Fassl A, Sicinski P.
europepmc +1 more source
Synergistic Strategies in Systemic Therapy for Advanced Hepatocellular Carcinoma
This article comprehensively examines the evolving landscape of systemic therapy for advanced hepatocellular carcinoma. It covers the progress in tyrosine kinase inhibitors and immune checkpoint inhibitors, analyzes the efficacy of novel combination strategies, and discusses current challenges like drug resistance and the lack of biomarkers.
Yongxin Yu +5 more
wiley +1 more source
Increased SOX10, p16, and Cyclin D1 Immunoreactivity Differentiates MAP Kinase-activated Low-grade Gliomas From Piloid Gliosis. [PDF]
Tang V +10 more
europepmc +1 more source
Abstract Large B‐cell lymphoma (LBCL) with IRF4 rearrangement (LBCL‐IRF4‐R) is a rare subtype predominantly diagnosed in children and young adults. Whether adult LBCL cases with IRF4 rearrangement (IRF4‐R) should be classified as LBCL‐IRF4‐R remains unclear. Clinicopathological and molecular features of 61 adult LBCL cases with IRF4‐R were analyzed and
Yuxiu Zhang +12 more
wiley +1 more source
Inhibition of Cyclin D1 by Novel Biguanide Derivative YB-004 Increases the Sensitivity of Bladder Cancer to Olaparib via Causing G0 / G1 Arrest. [PDF]
Xiao D +7 more
europepmc +1 more source
What's new? Colorectal cancer (CRC) frequently metastasizes to the liver, either synchronously with primary diagnosis or metachronously, after variable time intervals. Although implicated, the role of genetic factors in driving synchronous and metachronous disease progression remains uncertain.
Marie Rajtmajerova +16 more
wiley +1 more source
The Elevation of <i>IRSp53</i> Expressing Level in Colon Cancer Specimens and the Secretome of hAMSCs' Therapeutic Impacts on Tumor Growth Promotion via Inhibiting of EGFR/c-Src/IRSp53/p-AKT/p-Stat3/cyclin D1 Signaling Cascade in HT-29 Colon Cancerous Cell Line. [PDF]
Alavi M +3 more
europepmc +1 more source

