Results 231 to 240 of about 152,964 (318)

Cyclin D1 Overexpression in Rat Two-Stage Bladder Carcinogenesis and its Relationship with Oncogenes, Tumor Suppressor Genesand Cell Proliferation

, 1998
Chyi‐Chia Richard Lee, Shinji Yamamoto, Chikayoshi Masuda, Hideki Wanibuchi, Kazunobu Sugimura, Seiji Wada, Tatsuya Nakatani, Shinichi Ikemoto, Hidenori Kawashima, Rikyo Yoshimura, Kweske Yamamoto, Taketoshi Kishimoto, Shoji Fukushima   +12 more
openalex   +2 more sources

The Expression of Cyclins D1 and E in Predicting Short-Term Survival in Squamous Cell Carcinoma of the Lung [PDF]

, 2000
Rose C. Anton, Donna Coffey, Margaret Gondo, Mark A. Stephenson, Richard W. Brown, Philip T. Cagle   +5 more
openalex   +1 more source

The CRL7FBXW8 Complex Controls the Mammary Stem Cell Compartment through Regulation of NUMB Levels

Advanced Science, Volume 12, Issue 25, July 3, 2025.
In breast cancer (BC), NUMB loss of function (LOF) is common and mainly driven by protein hyper‐degradation. The CRL7FBXW8 complex is the E3 ligase responsible for NUMB degradation. Inhibition of CRL7FBXW8 in NUMB‐LOF BC cells restores NUMB levels, and decreases the number of cancer stem cells and tumorigenic ability in vivo. Targeting CRL7FBXW8 offers
Simone Sabbioni, Maria Grazia Filippone, Letizia Amadori, Stefano Confalonieri, Roberta Bonfanti, Stefano Capoano, Ivan Nicola Colaluca, Stefano Freddi, Giovanni Bertalot, Giovanni Fagà, Elisa Zagarrí, Mario Varasi, Rosalind Helen Gunby, Ciro Mercurio, Salvatore Pece, Pier Paolo Di Fiore, Daniela Tosoni   +16 more
wiley   +1 more source

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells. [PDF]

Invest Ophthalmol Vis Sci
Liu Q, Xia LX, Yi WZ, Wu YN, Gu SS, Chen JY, Liu TT, Lu YH, Cui YH, Meng J, Pan HW.   +10 more
europepmc   +1 more source

Cyclin D1, p16, and retinoblastoma gene regulate mitogenic signaling of endothelin in rat mesangial cells

, 1998
Yoshio Terada, Seiji Inoshita, Osamu Nakashima, Takehisa Yamada, Mimi Tamamori, Hiroshi Ito, Sei Sasaki, Fumiaki Marumo   +7 more
openalex   +1 more source

Increased Expression of Cyclin D1, Cyclin E and p21^Cip1 Associated with Decreased Expression of p27^Kip1 in Chemically Induced Rat Mammary Carcinogenesis [PDF]

, 2000
Tae Jung Jang, Myung Soo Kang, Heesoo Kim, Dong Hoon Kim, Jong Im Lee, Jung Ran Kim   +5 more
openalex   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

Advanced Science, Volume 12, Issue 26, July 10, 2025.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu   +13 more
wiley   +1 more source

Pharmacodynamics of Cyclin D1 Degradation in Ovarian Cancer Xenografts with Repeated Oral SHetA2 Dosing. [PDF]

AAPS J, 2023
Sharma A, Liu X, Chandra V, Rai R, Benbrook DM, Woo S.   +5 more
europepmc   +1 more source

Gut-enriched Kruppel-like factor represses cyclin D1 promoter activity through Sp1 motif [PDF]

, 2000
Jue‐Lon Shie
openalex   +1 more source

Transcriptomic Insights Into Serum‐Free Medium Adaptation and Temperature Reduction in Chinese Hamster Ovary Cell Cultures

Biotechnology Journal, Volume 20, Issue 7, July 2025.
Graphical Abstract and Lay Summary Transcriptomic analysis of CHO cells exposed to different industrially relevant conditions identified cholesterol and p53‐related genes with differential expression and several new housekeeping genes. ABSTRACT Chinese hamster ovary (CHO) cells are widely used in recombinant biopharmaceutical production; yet, yields ...
Benjamin F. Synoground, Yogender Gowtham, Timothy Lindquist, Junessa Pressley, Derrick C. Scott, Christopher S. Saski, Sarah W. Harcum   +6 more
wiley   +1 more source