Circ-PAN3 facilitates hepatocellular carcinoma growth via sponging miR-153 and upregulating cyclin D1. [PDF]
Yu S, Wang M, Li XU, Guo X, Qin R.
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The Oncoprotein Kinase Chaperone CDC37 Functions as an Oncogene in Mice and Collaborates with Both c-myc and Cyclin D1 in Transformation of Multiple Tissues [PDF]
Lilia Stepanova+4 more
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ABSTRACT Background Dysregulation of transcription factors is one of the most common factors for the pathogenesis of hepatocellular carcinoma (HCC). To the best of our knowledge, no study has yet investigated the clinical significance and functional role of STOX1 in HCC. Methods Real‐time PCR, Western blotting and immunohistochemistry were performed to
Chunlin Jiang+17 more
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Immunohistochemical Analysis of Cyclin D1 Shows Deregulated Expression in Multiple Myeloma with the t(11;14) [PDF]
Giancarlo Pruneri+11 more
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The role of cyclin D1 in lymphopoiesis
D Cyclins play an essential role connecting exogenous stimulation to the intrinsic cell cycle machinery. This family of proteins is composed of three members sharing a highly homologous domain, the cyclin box (coded by exons 1-3), which is responsible for their redundant role in the phosphorylation of the retinoblastoma protein upon association with ...
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Endometrial cancer is linked to obesity and chronic inflammation, potentially mediated by adipocytokines like adiponectin, leptin, IL6, and TNFα. This study examined mRNA expression of these markers and their receptors in cancerous versus benign endometrial tissue using qRT‐PCR.
Irene Ray+9 more
wiley +1 more source
MiR 329/449 Suppresses Cell Proliferation, Migration and Synergistically Sensitizes GBM to TMZ by Inhibiting Src/FAK, NF-kB, and Cyclin D1 Activity. [PDF]
Mendieta M+5 more
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Iron chelation is a promising yet underexplored strategy for colorectal cancer (CRC) treatment. Iron chelators have a dual role in inhibiting and potentially promoting cancer progression. Iron chelation affects key CRC pathways, including histone methylation, NDRG1 upregulation, Wnt/β‐catenin, and p53 modulation.
Gihani Vidanapathirana+4 more
wiley +1 more source
Simultaneous cyclin D1 overexpression and p27<sup>kip1</sup> knockdown enable robust Müller glia cell cycle reactivation in uninjured mouse retina. [PDF]
Wu Z+6 more
europepmc +1 more source
A potential mechanism for fumonisin B1-mediated hepatocarcinogenesis: cyclin D1 stabilization associated with activation of Akt and inhibition of GSK-3β activity [PDF]
Danica Ramljak+8 more
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