Results 281 to 290 of about 299,961 (316)
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Cyclin D1 transcriptional activation in MCL
Blood, 2014In this issue of Blood, Allinne et al propose the nucleolin-dependent activation of the translocated CCND1 allele in mantle cell lymphoma (MCL) because of its relocalization to a transcriptionally favorable area in the perinucleolar region.
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2016
Two proto-oncogenes from the Cyclin protein family that are involved in the regulation of the cell cycle are described in this chapter. Cyclin D1 gene or CCND1 is involved in the regulation of the cell cycle and becomes most abundant in the G1 phase in the lead up to DNA replication. The activity of the cyclin D in normal cell physiology contributes to
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Two proto-oncogenes from the Cyclin protein family that are involved in the regulation of the cell cycle are described in this chapter. Cyclin D1 gene or CCND1 is involved in the regulation of the cell cycle and becomes most abundant in the G1 phase in the lead up to DNA replication. The activity of the cyclin D in normal cell physiology contributes to
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Ras regulation of cyclin D1 promoter
2001Publisher Summary This chapter focuses on the Ras regulation of Cyclin D 1 promoter. Cyclin D l, the regulatory subunit of cyclin-dependent kinases (CDK) 4 and 6, is required for, and capable of, shortening, the G j phase of the cell cycle through the formation of holoenzyme complexes (cyclin-CDK) that phosphorylate retinoblastoma protein (pRB).
D F, Amanatullah +6 more
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β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
Nature, 1999O. Tetsu, F. McCormick
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Cyclin D1 in Human Neuroendocrine: Tumorigenesis
Annals of the New York Academy of Sciences, 2004Abstract: Human neuroendocrine tumors exhibit unique biological properties, and defining the molecular genetic alterations that underlie these distinctive features remains an important challenge. In addition to the MEN1 tumor suppressor gene, the cyclin D1 oncogene has demonstrated a role in the pathogenesis of parathyroid and gastroenteropancreatic ...
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Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication
Cell, 2023John Diffley
exaly
Cyclin E in normal physiology and disease states
Trends in Cell Biology, 2021Chen Chu, Yu Zhou, Piotr Sicinski
exaly
An update on the implications of cyclin D1 in oral carcinogenesis.
Oral Diseases, 2017P. Ramos-García +6 more
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American Journal of Surgical Pathology, 2017
Vignesh Shanmugam +5 more
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Vignesh Shanmugam +5 more
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