A simple cell-cycle control system in Marchantia polymorpha provides a framework for understanding plant cell proliferation. [PDF]
Romani F +7 more
europepmc +1 more source
Spatial Proteomics Identifies Distinct Synovial Microenvironments in Hip and Knee Osteoarthritis
Objective Osteoarthritis (OA) is a heterogeneous joint disease, yet mechanistic insights derive predominantly from knee OA and are often extrapolated to other joints. We investigated joint‐associated differences in the spatial molecular organization of hip and knee OA synovium.
Peng Xie +9 more
wiley +1 more source
Natural leaf shape variation reveals diverse transcriptional targets of GmJAG1 during soybean leaf development. [PDF]
Tamang BG, Kramer C, Ainsworth EA.
europepmc +1 more source
Video‐Assisted Intralesional Curettage for Invasive Nonmalignant Giant Cell Tumors
Abstract Giant cell tumor of bone is a locally aggressive benign neoplasm with a strong tendency for local recurrence after surgical treatment. Intralesional excision and curettage is preferred in most cases to maximize tumor removal while preserving the affected joint.
George Loria +5 more
wiley +1 more source
Cell-cycle genes in the mussel Mytilus galloprovincialis are cued by aerial heat stress in a fluctuating tidal environment. [PDF]
Hong HC +3 more
europepmc +1 more source
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source
Emodin-induced cell cycle arrest: A promising approach for cancer therapy (Review). [PDF]
Das S +8 more
europepmc +1 more source
What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
Genome-wide cyclin gene evolution in Arabidopsis and Brassica reveals polyploidization-driven duplication and flowering-time associations. [PDF]
Cantila AY +3 more
europepmc +1 more source
A Map Kinase Cascade Modulates Expression of Late G1 Phase Cyclins in Budding Yeast [PDF]
Expression of late G1 phase cyclins is the critical molecular event that marks commitment to enter the cell cycle. In budding yeast, late G1 phase cyclins initiate and sustain growth of a new daughter bud, so their expression also marks the start of a ...
Zebarjadi, Navid
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