Results 191 to 200 of about 141,408 (359)
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai+7 more
wiley +1 more source
Emerging concepts in cancer therapy: Mechanisms of resistance
Cancer Reports, Volume 5, Issue 12, December 2022.
Seema Gupta+2 more
wiley +1 more source
Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. [PDF]
Sharon Bodrug+5 more
openalex +1 more source
Die Erzeugung funktionalisierter Ubiquitinbausteine mittels Expression in E. coli bietet Zugang zu verschiedenen Di‐, Tri‐ und Tetra‐Ubiquitinketten. Photoinitiierte Thiol‐En‐Klickreaktionen werden dabei in Kombination mit einer Maskierungs‐ und Schutzgruppenstrategie zum kontrollierten Aufbau von Ubiquitinketten sowie zur Semisynthese von ...
Moritz Urschbach+6 more
wiley +1 more source
Alcohol extracts of Chinese bayberry branch induce S‐phase arrest and apoptosis in HepG2 cells
The alcohol extracts of Chinese bayberry Myrica rubra branches (MRBE) effectively inhibited the proliferation of HepG2 cells by inducing cell cycle arrest in S phase and promoting apoptosis, with this arrest potentially mediated by the activation of p21–Cyclin–CDK (cyclin‐dependent kinase) complex signaling pathways.
Yuanyuan Zheng+8 more
wiley +1 more source
Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2.
James R. Bischoff+4 more
openalex +1 more source
Generating functionalized ubiquitin building blocks via expression in E. coli paves the way to different di‐, tri‐, and tetra‐ubiquitin chains. Light‐induced thiol‐ene click reactions, combined with a masking and protection strategy, are harnessed to establish controlled ubiquitin chain assembly and to allow the semisynthesis of site‐selectively ...
Moritz Urschbach+6 more
wiley +1 more source
Abstract Chromosomal instability is a common feature in malignant tumors. Previous studies have indicated that inactivation of the classical tumor suppressor genes RB1, CDKN2A, and TP53 may contribute to chromosomal aberrations in cancer by disrupting different aspects of the cell cycle and DNA damage checkpoint machinery.
Natalie Andersson+6 more
wiley +1 more source
Cyclin G is a transcriptional target of the p53 tumor suppressor protein. [PDF]
Koji Okamoto, David Beach
openalex +1 more source