Results 201 to 210 of about 33,178 (262)

Olig1/2 Drive Astrocytic Glioblastoma Proliferation Through Transcriptional Co-Regulation of Various Cyclins. [PDF]

Genes (Basel)
Tian Y, Wang Z, Sun M, Li J, Zheng W, Yang F, Zhang Z.   +6 more
europepmc   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Targeting CDK2 and other novel cell cycle targets for breast cancer therapy. [PDF]

Expert Opin Ther Targets
Chen MK, Luo L, Massoumi N, Keyomarsi K.
europepmc   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

The B-type cyclin Clb4 prevents meiosis I sister centromere separation in budding yeast. [PDF]

G3 (Bethesda)
Lumbroso G, Cairo G, Lacefield S, Murray AW.   +3 more
europepmc   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

Medicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino, Manuela Bartolini, Rudolf Andrys, Kamil Musilek   +3 more
wiley   +1 more source

Coupling of stemness maintenance with cell cycle control in stem cells. [PDF]

Front Cell Dev Biol
Huang X, Wang Y, Li Q, Li X, Wang C.
europepmc   +1 more source

Targeting CDK2 for cancer therapy. [PDF]

Cell Rep
Knudsen ES, Witkiewicz AK, Sanidas I, Rubin SM.   +3 more
europepmc   +1 more source

Differences in Binding Affinity Among Cell-cycle CDK and Cyclin Pairs. [PDF]

J Mol Biol
Putta S, Villegas CA, Rubin SM.
europepmc   +1 more source

Capacity for Compensatory Cyclin D2 Response Confers Trametinib Resistance in Canine Mucosal Melanoma. [PDF]

Cancers (Basel)
Wei BR, Verdi V, Zhang S, Mock BA, Shive HR, Simpson RM.   +5 more
europepmc   +1 more source