Results 241 to 250 of about 141,408 (359)

Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors. [PDF]

open access: yesGenome Biol
Merk DJ   +25 more
europepmc   +1 more source

HN1 expression contributes to mitotic fidelity through Aurora A‐PLK1‐Eg5 axis

open access: yesCytoskeleton, EarlyView.
Abstract Hematological and neurological expressed 1 (HN1) is homolog of Jupiter protein from Drosophila melanogaster where it functions as a microtubule‐associated protein. However, in mammalian cells, HN1 is associated partially with y‐tubulin in centrosomes, Stathmin for stabilizing microtubules, and Cdh1 for regulating Cyclin B1 for cell cycle ...
Gülseren Özduman   +3 more
wiley   +1 more source

A Requirement for Cyclin D3–Cyclin-dependent Kinase (cdk)-4 Assembly in the Cyclic Adenosine Monophosphate–dependent Proliferation of Thyrocytes [PDF]

open access: bronze, 1998
Fabienne Depoortere   +8 more
openalex   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

open access: yesCytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source

Positively charged specificity site in cyclin B1 is essential for mitotic fidelity. [PDF]

open access: yesNat Commun
Heinzle C   +9 more
europepmc   +1 more source

Repression of cyclin D1: a novel function of MYC.

open access: green, 1994
A Philipp   +7 more
openalex   +1 more source

Lamellarin D Acts as an Inhibitor of Type I Collagen Production

open access: yesChemMedChem, EarlyView.
COL1A2 gene, encoding type I collagen, is a key target for pulmonary fibrosis. We established a screening system to identify small molecules that inhibit COL1A2 gene expression. Using this system, we screen a library of compounds and identify lamellarin D as a potent inhibitor of COL1A2 expression, suggesting lamellarin D is a promising new lung ...
Daisuke Okuno   +19 more
wiley   +1 more source

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