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Trends in Biochemical Sciences, 1995
D-type cyclins couple extracellular signals to the biochemical machinery that governs progression through G1 phase of the mammalian cell division cycle. Induced by growth factor stimulation, D-type cyclins assemble with cyclin-dependent kinases CDK4 and CDK6 to form holoenzymes that facilitate exit from G1 by phosphorylating key substrates, including ...
C. Sherr
semanticscholar +3 more sources
D-type cyclins couple extracellular signals to the biochemical machinery that governs progression through G1 phase of the mammalian cell division cycle. Induced by growth factor stimulation, D-type cyclins assemble with cyclin-dependent kinases CDK4 and CDK6 to form holoenzymes that facilitate exit from G1 by phosphorylating key substrates, including ...
C. Sherr
semanticscholar +3 more sources
Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
Cell, 1994Tony Hunter
exaly +2 more sources
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
Cell, 1992Philip W Hinds +2 more
exaly +2 more sources
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
Cell, 1993Charles J Sherr
exaly +2 more sources
Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast
Cell, 1991Vjekoslav Dulic
exaly +2 more sources
Physical interaction of the retinoblastoma protein with human D cyclins
Cell, 1993Philip W Hinds, Kenway Louie
exaly +2 more sources
Seminars in Cell and Developmental Biology, 2020
Proper progression throughout the cell division cycle depends on the expression level of a family of proteins known as cyclins, and the subsequent activation of cyclin-dependent kinases (Cdks).
Diego Martínez-Alonso, Marcos Malumbres
semanticscholar +1 more source
Proper progression throughout the cell division cycle depends on the expression level of a family of proteins known as cyclins, and the subsequent activation of cyclin-dependent kinases (Cdks).
Diego Martínez-Alonso, Marcos Malumbres
semanticscholar +1 more source
The International Journal of Biochemistry & Cell Biology, 2004
E-type cyclins (cyclin E1 and cyclin E2) are expressed during the late G1 phase of the cell cycle until the end of the S-phase. The activity of cyclin E is limiting for the passage of cells through the restriction point "R" which marks a "point of no return" for cells entering the division cycle from a resting state or passing from G1 into S-phase ...
Tarik, Möröy, Christoph, Geisen
openaire +2 more sources
E-type cyclins (cyclin E1 and cyclin E2) are expressed during the late G1 phase of the cell cycle until the end of the S-phase. The activity of cyclin E is limiting for the passage of cells through the restriction point "R" which marks a "point of no return" for cells entering the division cycle from a resting state or passing from G1 into S-phase ...
Tarik, Möröy, Christoph, Geisen
openaire +2 more sources