Results 251 to 260 of about 37,065 (297)

Plant cyclins: a unified nomenclature for plant A-, B- and D-type cyclins based on sequence organization

open access: yesPlant Molecular Biology, 1996
The comparative analysis of a large number of plant cyclins of the A/B family has recently revealed that plants possess two distinct B-type groups and three distinct A-type groups of cyclins [1].
Jean-Pierre Renaudin   +2 more
exaly   +2 more sources

Cyclins in aspergilli: Phylogenetic and functional analyses of group I cyclins

open access: yesStudies in Mycology, 2018
We have identified the cyclin domain-containing proteins encoded by the genomes of 17 species ofAspergillusas well as 15 members of other genera of filamentous ascomycetes. Phylogenetic analyses reveal that the cyclins fall into three groups, as in other
Tetsuya Horio, Berl R Oakley
exaly   +2 more sources

Cyclins, cyclin‐dependent kinases and differentiation

BioEssays, 1997
AbstractCyclin‐dependent kinases and their regulatory subunits, the cyclins, are known to regulate progression through the cell cycle. Yet these same proteins are often expressed in non‐cycling, differentiated cells. This review surveys the available information about cyclins and cyclin‐dependent kinases in differentiated cells and explores the ...
C Y, Gao, P S, Zelenka
openaire   +2 more sources

Cyclin E

The International Journal of Biochemistry & Cell Biology, 2004
E-type cyclins (cyclin E1 and cyclin E2) are expressed during the late G1 phase of the cell cycle until the end of the S-phase. The activity of cyclin E is limiting for the passage of cells through the restriction point "R" which marks a "point of no return" for cells entering the division cycle from a resting state or passing from G1 into S-phase ...
Tarik, Möröy, Christoph, Geisen
openaire   +2 more sources

Viral cyclins

Reviews in Medical Virology, 2000
Cyclins are regulatory subunits of the cyclin-dependent protein kinases (CDKs). Members of this serine-threonine kinase family regulate the progression of cells through the division cycle. Until some years ago, cyclins were presumed to be encoded exclusively by eukaryotic cells.
S, Mittnacht, C, Boshoff
openaire   +2 more sources

A proliferation of cyclins

Trends in Cell Biology, 1992
Cyclins are regulatory subunits of the serine/threonine protein kinases that play key roles in cell cycle control. The roster of known cyclins has expanded significantly in the past year, revealing a large and very diverse family of proteins. Although cyclins were originally characterized by their periodic accumulation during interphase and destruction
D J, Lew, S, I Reed
openaire   +2 more sources

Mouse Development and Cell Proliferation in the Absence of D-Cyclins

open access: yesCell, 2004
D-type cyclins (cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. We tested the requirement for D-cyclins in mouse development and in proliferation by generating mice lacking all D-cyclins.
Maria A Ciemerych   +2 more
exaly   +2 more sources

Cyclins, Cyclin-Dependent Kinases, and Cyclin-Dependent Kinase Inhibitors in the Mouse Nervous System

Molecular Neurobiology, 2020
Development and normal physiology of the nervous system require proliferation and differentiation of stem and progenitor cells in a strictly controlled manner. The number of cells generated depends on the type of cell division, the cell cycle length, and the fraction of cells that exit the cell cycle to become quiescent or differentiate. The underlying
Alice Grison, Suzana Atanasoski
openaire   +4 more sources

Cyclins and Cyclin-Dependent Kinases: Theme and Variations

1995
Publisher Summary This chapter introduces cyclins and their partner—cyclin dependent kinases (CDKs)—and the ways in which CDK complexes can be regulated. Cyclins are intimately concerned with regulating and coordinating deoxyribonucleic acid (DNA) replication and cell division.
openaire   +2 more sources

Expression of cyclins, cyclin-dependent kinases and cyclin-dependent kinase inhibitors in oligodendrogliomas in humans

Neuroscience Letters, 2003
Cyclins are regulatory proteins of the cell cycle which bind and activate kinases. In gliomas, contrary to many malignancies, cyclin D1 is rarely amplified, but together with other cyclins, it increases with anaplasia. In a series of 23 surgical biopsies of grade II and III oligodendroglioma, cyclin D1, E, A, B1, CDK4-6, CDK2, Cdc2 and p27/Kip.1 have ...
Valentina, Fiano   +2 more
openaire   +2 more sources

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