Results 41 to 50 of about 544 (162)

Effect of exogenous abscisic acid on accumulation of raffinose family oligosaccharides and galactosyl cyclitols in tiny vetch seeds (Vicia hirsuta [L.] S.F. Gray)

open access: yesActa Societatis Botanicorum Poloniae, 2011
The role of the abscisic acid (ABA) in biosynthesis of raffinose family oligosaccharides (RFOs) and galactosyl cyclitols (Gal-C) in tiny vetch (Vicia hirsuta [L.] S.F. Gray) seeds was investigated.
Lesław B. Lahuta   +3 more
doaj   +1 more source

A Practical and Flexible De Novo Synthesis of Deoxygenated Carbasugars and Their Cyclitol Epoxides

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 18, 14 May 2026.
A de novo synthesis route comprising enantioselective Brown crotylation and ring‐closing metathesis as the key steps enables the synthesis of a‐ and b‐carba‐paratose, a‐ and b‐carba‐colitose as well as four configurational deoxycyclophellitol isosteres.
Yevhenii Radchenko   +4 more
wiley   +1 more source

Untargeted Metabolomic and Lipidomic Profiles of Gingival Crevicular Fluid in the Context of Periodontitis

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 5, Page 774-783, May 2026.
ABSTRACT Aim(s) This cross‐sectional clinical study aimed to explore the untargeted metabolomic and lipidomic profiles in gingival crevicular fluid (GCF) obtained from healthy individuals and patients with periodontitis. Materials and Methods GCF was collected from 17 periodontally healthy and 19 periodontitis patients.
Caroline H. Henderzahs   +6 more
wiley   +1 more source

Changes in soluble carbohydrates during storage of Caesalpinia echinata LAM. (Brazilwood) seeds, an endangered leguminous tree from the Brazilian Atlantic Forest

open access: yesBrazilian Journal of Biology
Caesalpinia echinata seeds stored in laboratory environmental conditions lose their viability in one month whilst under low temperatures germination is maintained for 18 months of storage.
I. S. Garcia   +4 more
doaj   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel   +2 more
wiley   +1 more source

L‐Quebrachitol Enhances Sedative Effect of Diazepam Through GABAergic Pathway: Animal and Computational Studies

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
L‐quebrachitol (LQL) significantly enhanced the sedative effects of diazepam in thiopental sodium‐induced chicks by reducing sleep latency and prolonging duration. Molecular docking revealed LQL's interaction with GABAA receptor (α1 and β2 subunits), supporting a GABAergic mechanism and highlighting its potential as a safe, natural sedative agent ...
Asifa Asrafi   +9 more
wiley   +1 more source

High metabolic sensitivity to hot drought in two declining pine species with constrained physiology

open access: yesFunctional Ecology, Volume 40, Issue 1, Page 239-255, January 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Decline syndromes preceding tree mortality under increased abiotic stress often include reductions in transpiring leaf area and tree growth. However, the mechanisms regulating the metabolism and physiology of declining trees before they cross irreversible thresholds in ...
Guillermo Gea‐Izquierdo   +6 more
wiley   +1 more source

Millimetre‐Scale Stratification of Microbial Communities in Hydrothermal Sediments

open access: yesEnvironmental Microbiology, Volume 28, Issue 1, January 2026.
Zooming into the millimetre‐scale spatial distribution of organic molecules in hydrothermally impacted sediments using mass spectrometry imaging reveals a distinct lipid zonation with abrupt transitions at critical redox interfaces. This zonation reflects a pronounced stratification of diverse microbial communities and highlights surprisingly ...
Janina Groninga   +5 more
wiley   +1 more source

Optimization of Hyperglycemic Induction in Zebrafish and Evaluation of Its Blood Glucose Level and Metabolite Fingerprint Treated with Psychotria malayana Jack Leaf Extract

open access: yesMolecules, 2019
A standard protocol to develop type 1 diabetes in zebrafish is still uncertain due to unpredictable factors. In this study, an optimized protocol was developed and used to evaluate the anti-diabetic activity of Psychotria malayana leaf.
Khaled Benchoula   +10 more
doaj   +1 more source

A Comprehensive Study of Biohopanoid Production in Alphaproteobacteria: Biosynthetic, Chemotaxonomical, and Geobiological Implications

open access: yesGeobiology, Volume 23, Issue 6, November/December 2025.
ABSTRACT Bacteriohopanepolyol derivatives (BHPDs) and dia‐ and catagenetic products formed from these bacterial membrane modifiers are extensively used as biomarkers in molecular ecological and geoscience studies. Some BHPDs can be assigned to specific phylogenetic bacterial groups. With the vastly increasing availability of complete bacterial genomes,
Jaap S. Sinninghe Damsté   +5 more
wiley   +1 more source

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