Results 51 to 60 of about 2,129 (203)

Stereocontrolled Total Synthesis of Tetrodotoxin from Inositol and D-Glucose by Three Routes: Aspects for Constructing Complex Multi-Functionalized Cyclitols with Branched-Chain Structures

Natural Product Communications, 2013
This report describes the stereocontrolled total synthesis of the multi-functionalized cyclitol derivative tetrodotoxin containing eight asymmetric carbons and different types of branched-chains from myo -inositol and D-glucose using three different ...
Ken-ichi Sato, Shoji Akai, Juji Yoshimura   +2 more
doaj   +1 more source

Effect of exogenous abscisic acid on accumulation of raffinose family oligosaccharides and galactosyl cyclitols in tiny vetch seeds (Vicia hirsuta [L.] S.F. Gray)

Acta Societatis Botanicorum Poloniae, 2011
The role of the abscisic acid (ABA) in biosynthesis of raffinose family oligosaccharides (RFOs) and galactosyl cyclitols (Gal-C) in tiny vetch (Vicia hirsuta [L.] S.F. Gray) seeds was investigated.
Lesław B. Lahuta, Ryszard J. Górecki, Ewa Gojło, Marcin Horbowicz   +3 more
doaj   +1 more source

Untargeted Metabolomic and Lipidomic Profiles of Gingival Crevicular Fluid in the Context of Periodontitis

Journal of Clinical Periodontology, Volume 53, Issue 5, Page 774-783, May 2026.
ABSTRACT Aim(s) This cross‐sectional clinical study aimed to explore the untargeted metabolomic and lipidomic profiles in gingival crevicular fluid (GCF) obtained from healthy individuals and patients with periodontitis. Materials and Methods GCF was collected from 17 periodontally healthy and 19 periodontitis patients.
Caroline H. Henderzahs, Chiaki Yamada, Alexandr Morozov, Thelmalane Yalartai, Vanchit John, Hawra AlQallaf, Alexandru Movila   +6 more
wiley   +1 more source

COX-2 inhibitors from stem bark of Bauhinia rufescens Lam. (Fabaceae) [PDF]

Chemical investigation of the stem bark of Bauhinia rufescens resulted in the isolation of a new cyanoglucoside and menisdaurin from methanol extract and oxepin from petroleum ether extract.
Muhammad, Aminu, Sirat, Hasnah Mohd
core   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Precision Activity‐Based α‐Amylase Probes for Dissection and Annotation of Linear and Branched‐Chain Starch‐Degrading Enzymes

Angewandte Chemie, Volume 137, Issue 5, January 27, 2025.
Activity‐based probes were designed as a method to annotate substrate specificity of retaining α‐amylases. Fluorescent probes were used in activity‐based protein profiling experiments with pure protein, a prominent gut microbe and in a species‐rich composter sample.
Isabelle B. Pickles, Yurong Chen, Olga Moroz, Haley A. Brown, Casper de Boer, Zachary Armstrong, Nicholas G. S. McGregor, Marta Artola, Jeroen D. C. Codée, Nicole M. Koropatkin, Herman S. Overkleeft, Gideon J. Davies   +11 more
wiley   +2 more sources

The greenhouse diet : gypsy moth performance in a CO2-enriched world [PDF]

, 2008
Rising atmospheric CO2 is regarded as the main driver of global warming (Crowley, 2000). While temperature changes directly affect plants and animals (Root et al., 2003; Parmesan, 2006), the effects of CO2 on herbivores are mediated through changes in ...
Schafellner, Christa, Schopf, Axel
core  

L‐Quebrachitol Enhances Sedative Effect of Diazepam Through GABAergic Pathway: Animal and Computational Studies

Brain and Behavior, Volume 16, Issue 1, January 2026.
L‐quebrachitol (LQL) significantly enhanced the sedative effects of diazepam in thiopental sodium‐induced chicks by reducing sleep latency and prolonging duration. Molecular docking revealed LQL's interaction with GABAA receptor (α1 and β2 subunits), supporting a GABAergic mechanism and highlighting its potential as a safe, natural sedative agent ...
Asifa Asrafi, Mohammad Aslam, Md. Sakib Al Hasan, Mohammed Burhan Uddin, Emon Mia, Mohammad Y. Alshahrani, Sumaya Akter Bithi, Mst. Sumaia Akter, Md. Arif Hossain, Md. Torequl Islam   +9 more
wiley   +1 more source

High metabolic sensitivity to hot drought in two declining pine species with constrained physiology

Functional Ecology, Volume 40, Issue 1, Page 239-255, January 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Decline syndromes preceding tree mortality under increased abiotic stress often include reductions in transpiring leaf area and tree growth. However, the mechanisms regulating the metabolism and physiology of declining trees before they cross irreversible thresholds in ...
Guillermo Gea‐Izquierdo, María B. Fernández de Simón, David Sánchez‐Gómez, Dario Martin‐Benito, Antonio J. Pérez‐Luque, Iria Muiño, Ismael Aranda   +6 more
wiley   +1 more source

Changes in soluble carbohydrates during storage of Caesalpinia echinata LAM. (Brazilwood) seeds, an endangered leguminous tree from the Brazilian Atlantic Forest

Brazilian Journal of Biology
Caesalpinia echinata seeds stored in laboratory environmental conditions lose their viability in one month whilst under low temperatures germination is maintained for 18 months of storage.
I. S. Garcia, A. Souza, C. J. Barbedo, S. M. C. Dietrich, R. C. L. Figueiredo-Ribeiro   +4 more
doaj   +1 more source