Synthesis of pyrrolizines by intramolecular capture of 1,4-dipolar intermediates in reactions of enamines with dimethyl acetylenedicarboxylate [PDF]
Solvent polarity and reaction temperature strongly influence the reactions of dimethyl acetylenedicar-boxylate (DMAD) with 1-pyrrolidinyl enamines of acyclic and cyclic ketones. Whereas DMAD and 1-[1-phenyl-2-(phenylthio)ethenyl]pyrrolidine (3) give only
Harkema, S.+5 more
core +3 more sources
Cycloaddition of Diphenylnitrilimine to 1,5-Benzodiazepines [PDF]
The cycloaddition reaction of diphenylnitrilimine on the 1,5-benzodiazepines has been studied. New molecules of triazolobenzodiazepines type have been isolated and characterized.
Rachid Zinber+4 more
doaj
Network-analysis-guided synthesis of weisaconitine D and liljestrandinine. [PDF]
General strategies for the chemical synthesis of organic compounds, especially of architecturally complex natural products, are not easily identified. Here we present a method to establish a strategy for such syntheses, which uses network analysis.
Gallego, GM+8 more
core +2 more sources
The single-crystal-to-single-crystal (scsc) synthesis of a 2D polymer based on photochemically triggered [2 + 2]-cycloaddition is reported. Both monomer and polymer single crystals are analyzed by X-ray diffraction, which is the first case of a scsc two ...
Ralph Z. Lange+3 more
semanticscholar +1 more source
Preparation of 4 '-spirocyclobutyl nucleoside analogues as novel and versatile adenosine scaffolds
Despite the large variety of modified nucleosides that have been reported, the preparation of constrained 4 '-spirocyclic adenosine analogues has received very little attention.
De Vleeschouwer, Freija+10 more
core +1 more source
Synthesis and reactivity of spiro-fused β-lactams [PDF]
A
D'hooghe, Matthias+2 more
core +2 more sources
A surprising steric effect on a tandem cycloaddition/ring-opening reaction : rapid syntheses of difluorinated analogues of (hydroxymethyl)conduritols [PDF]
Difluorinated analogues of (hydroxymethyl)conduritols can be synthesised from selected furans and a difluorinated dienophile in two reaction ...
Fawcett, J.+5 more
core +1 more source
Promotion mechanism of hydroxyl groups in catalyzing CO2 cycloaddition
In this study, a series of hydroxy-functionalized quaternary ammonium salt catalysts, i.e., NEt3(HE)Br, NEt2(HE)2Br, NEt1(HE)3Br, and N(HE)4Br, were successfully prepared by quantitatively grafting hydrogen-bond donors (HBDs) as electrophilic sites on ...
Yiming Wang+5 more
doaj
Catalytic enantioselective synthesis of quaternary carbon stereocentres. [PDF]
Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single ...
Overman, Larry E, Quasdorf, Kyle W
core
A Palladium-Catalyzed Vinylcyclopropane (3 + 2) Cycloaddition Approach to the Melodinus Alkaloids [PDF]
A palladium-catalyzed (3 + 2) cycloaddition of a vinylcyclopropane and a β-nitrostyrene is employed to rapidly assemble the cyclopentane core of the Melodinus alkaloids.
Goldberg, Alexander F. G.+1 more
core +2 more sources