Results 151 to 160 of about 27,486 (241)

Breaking the Mold: Electrophilic Hydrophosphanation Emerges

Chemistry – A European Journal, EarlyView.
Electrophilic hydride attack on the olefin, instead of the classical nucleophilic addition by a phosphanido ligand, is unveiled in rhodium‐catalyzed olefin hydrophosphanation. This hydride‐driven pathway operates for both activated and inactivated olefins, with transition states characterized by elongated Rh─H bonds and nascent C─H bond formation ...
Víctor Varela‐Izquierdo, Janeth Navarro, Judit Cano‐Asensio, José A. López, Cristina Tejel   +4 more
wiley   +1 more source

Collective asymmetric synthesis of the Strychnos alkaloids via thiophene S,S-dioxide cycloadditions. [PDF]

Nat Chem
Park KH', Park J, Frank N, Zhang H, Tian P, Biddick Y, Duarte F, Anderson EA.   +7 more
europepmc   +1 more source

Synthesis and Reactivity of 3‐Aminosydnones in Cycloaddition Reactions With Alkynes

Chemistry – A European Journal, EarlyView.
The synthesis, functionalization, and reactivity as dipoles of 3‐aminosydnones have been investigated. These neglected compounds undergo smooth cycloaddition reactions with strained alkynes, leading to 1‐aminopyrazoles. ABSTRACT We present in this article the synthesis, functionalization, and properties of 3‐aminosydnones, a forgotten class of ...
Apolline Dominic, Timothée D'anfray, Guillaume Force, David‐Alexandre Buisson, Maxime Tricoire, Alexis Leblais, Davide Audisio, Frédéric Taran   +7 more
wiley   +1 more source

Catalytic Generation of Cationic Gold Carbene Complexes From 7‐Alkynylnorbornadienes and Their Intermolecular Cyclopropanation With Alkenes

Chemistry – A European Journal, EarlyView.
Efficient cationic gold(I)‐catalyzed intermolecular cyclopropanation of 7‐alkynylnorbornadiene derivatives has been developed. This methodology offers the synthesis of a new class of norbornene derivatives in high yield with excellent diastereoselectivity.
Kento Ishida, Kenta Toei, Fumiaki Tomi, Norio Sakai   +3 more
wiley   +1 more source

Safe by Design Flow Technology for Diazoacetonitrile Generation and Direct Conversion to Pyrazoles. [PDF]

ChemistryOpen
Bošković D, Loebbecke S, Piscopo CG, Radulescu LJ, Schwarzer M.   +4 more
europepmc   +1 more source

N‐Aryl Acridone Derivatives as Effective Catalysts for Energy Transfer Reactions

Chemistry – A European Journal, EarlyView.
Acridones derivatives have high triplet energy, are simple accessible, and could be used in challenging [2+2] ENT reactions. ABSTRACT Organic photocatalysts capable of promoting high‐energy triplet energy transfer (EnT) remain limited, particularly for demanding [2+2] photocycloaddition reactions.
Francesco Calogero, Gaetano D'Onghia, Federica Fina, Zakaria Ziani, Luca Sensoli, Andrea Gualandi, Andrea Fermi, Paola Ceroni, Pier Giorgio Cozzi   +8 more
wiley   +1 more source

Synthesis and Biological Evaluation of Well‐Defined M6P(n)‐Modified Glycopeptides for Targeted Protein Degradation

Chemistry – A European Journal, EarlyView.
A synthetic methodology has been developed to prepare multifunctional M6P and M6Pn ligands of different valency. The glycopeptides were conjugated to cetuximab and then examined to mediate cellular uptake of fluorescently labeled EGFRvIII. Only cetuximab modified by glycopeptides having 3 or 6 M6P or M6Pn residues demonstrated greater uptake.
Patrycja Lenartowicz, Jan‐Willem H. Langenbach, Nataliia Voloshyna, David Aidukas, Arwin J. Brouwer, John A. W. Kruijtzer, Geert‐Jan Boons   +6 more
wiley   +1 more source

Triplet Energy Transfer-Mediated Intermolecular Paternò-Büchi Reaction for the Synthesis of Trifluoromethylated Oxetanes. [PDF]

Org Lett
Zhu Y, Fernandes AJ, Zhilin E, Katayev D.   +3 more
europepmc   +1 more source

SO2 Transfer Enabled by an Easy‐to‐Handle Ionic Liquid

Chemistry – A European Journal, EarlyView.
Best of both worlds: The ionic liquid [NEt3Me][Cl(SO2)n] unites the atom economy and low cost of sulfur dioxide with the safety and applicability of common surrogates, streamlining SO2 transfer to access to 3‐sulfolenes, sulfonamides, and SuFEx reagents.
Johanna S. Sturm, Letizia Lanfredi, Severin Erbertseder, Marius Balizs, Patrick Voßnacker, Simon Steinhauer, Merlin Kleoff, Anja Wiesner, Niklas Limberg, Patrick Pröhm, Franz‐Lucas Haut, Sebastian Riedel   +11 more
wiley   +1 more source

Total Synthesis of (+)-Raistrickindole A. [PDF]

Org Lett
Jackson AC, Cho YS, Hwang T, Park J, Wood JL.   +4 more
europepmc   +1 more source