Results 151 to 160 of about 27,451 (245)
Triazenyl Furans as Diels-Alder Dienes. [PDF]
Budwitz JE +3 more
europepmc +1 more source
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis +2 more
wiley +1 more source
Electrochemical and photocatalytic generation of cis-olefin-bridged carbodication for umpolung [4+1] cycloaddition. [PDF]
Matsuyama H +4 more
europepmc +1 more source
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar +13 more
wiley +1 more source
Copper-catalyzed enantioselective interrupted azide-alkyne cycloaddition to access axially chiral diaryl ethers. [PDF]
Wu R +8 more
europepmc +1 more source
Tetrazine Ligation in Living Systems: Beyond Fast Kinetics to Effective Bioorthogonality
Rapid reaction kinetics (k2) alone do not ensure successful tetrazine ligation in living systems. This review introduces ‘effective orthogonality’—focusing on chemical survival, availability, and encounter—as a practical framework. We highlight how bottlenecks shift from cellular sinks to in vivo delivery limits, offering design strategies for reliable
Junhyeong Yim +3 more
wiley +1 more source
Catalytic Activity of Ruthenium Complexes Containing Hydrotris(pyrazolyl)methane or Cyclopentadienyl Ligands in the Azide-Alkyne Click Cycloaddition Reaction. [PDF]
López-Sánchez B +7 more
europepmc +1 more source

