Results 201 to 210 of about 82,507 (282)

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Switchable Reactivity of Hydrazonoyl Halides: Enabling the Discovery of Potent Hypoxia-Inducible Factor Inhibitors. [PDF]

JACS Au
Tian X, Wu H, Shi Y, Cui X, Pang R, Zhang B, Zhou R, Lu L, Yang YF, Wang Y.   +9 more
europepmc   +1 more source

Substrate stiffness regulates cell fate and its applications in the repair of motor system: From two dimensions to three dimensions

BMEMat, EarlyView.
Substrate stiffness with different dimensions (2D and 3D) exerts a regulatory role in cellular behaviors, thereby governing cell fate decisions. Biomaterials with tunable stiffness exhibit substantial functional potential for the repair and regeneration of the motor system.
Zhiyuan Lu, Renwang Sheng, Ludvig J. Backman, Chuanquan Liu, Danning Zheng, Wei Zhang, Jialin Chen   +6 more
wiley   +1 more source

Understanding the Electronic Structure and Diels-Alder Reactivity of Nitrilium-Type <i>N</i>-Hetarynes. [PDF]

J Org Chem
González-Pinardo D, Fernández I.
europepmc   +1 more source

Enabling Cross‐Coupling Reactivity of α‐Pentafluorosulfanyl Compounds with a Thermally Stable Organozinc α‐SF5 Reagent

Chemistry – A European Journal, EarlyView.
This work describes the first example of a thermally stable α‐SF5 organometallic reagent, which allows for extensive downstream functionalization by allylation and acylation reactions under copper catalysis, as well as palladium‐catalyzed Negishi‐type cross‐coupling conditions up to 96% yield. In silico analysis shines initial light on the requirements
Lujie Xu, David Rombach
wiley   +1 more source

Recent Breakthroughs in Cyclizations of <i>Ortho</i>-Quinone Methides. [PDF]

Molecules
Wang D, Guo J, Tan L, Qiu L, Reddy CVS, Xia W.   +5 more
europepmc   +1 more source

Photochemical and Thermal Activation of a Diarylbismuth Azide

Chemistry – A European Journal, EarlyView.
We report the synthesis and characterization of a novel diarylbismuth azide and its divergent reactivity upon thermal or photochemical activation. These findings contribute expanding the reactivity landscape of heavy pnictogen compounds and sets the basis for further investigations. ABSTRACT Azides are widely employed in synthesis as convenient nitrene
Giacomo Pugliese, Oliver Pichl, Gregor Schnakenburg, Peter Vöhringer, Luis I. Domenianni, Alessandro Bismuto   +5 more
wiley   +1 more source

Stereoselective dearomative formal [3 + 2] cycloaddition of indole with allenols: access to structurally diverse cyclopenta[<i>b</i>]indoles. [PDF]

Chem Sci
Kaur K, Singh P, Thombare RD, P AK, Mane MV, Shaikh AC.   +5 more
europepmc   +1 more source

Persilylated and Related Silyl Anion‐Induced Synthesis of Group 3–10 Metal–Silyl Complexes

Chemistry – A European Journal, EarlyView.
Persilylated and related silyl anions serve as powerful tools for constructing metal–silyl complexes across group 3–10 elements. Their strong σ‐donating ability and steric bulk stabilize low‐coordinate, reactive species and enable unique bonding motifs.
Yusuke Sunada
wiley   +1 more source